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一名年轻男性患者小肠嗜酸性粒细胞性胃肠炎酷似嗜酸性肉芽肿性多血管炎

Eosinophilic Gastroenteritis in the Small Intestine Mimicking Eosinophilic Granulomatosis With Polyangiitis in a Young Male Patient.

作者信息

Hayashi Maika, Ohta Ryuichi, Yamane Fumiko, Mishiro Tsuyoshi, Sano Chiaki

机构信息

Family Medicine, Shimane University Faculty of Medicine, Izumo, JPN.

Community Care, Unnan City Hospital, Unnan, JPN.

出版信息

Cureus. 2022 Oct 1;14(10):e29813. doi: 10.7759/cureus.29813. eCollection 2022 Oct.

DOI:10.7759/cureus.29813
PMID:36337807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9621689/
Abstract

Eosinophilic gastroenteritis (EGE) is a disease involving the gastrointestinal tract that involves the invasion of eosinophils into the lumen of the tract. Invasion of eosinophils in the tract causes edema and inflammation of the wall, resulting in acute or chronic diarrhea and abdominal pain. EGE can cause chronic inflammation in the small intestine, thereby mimicking chronic vasculitis. We report the case of a 24-year-old male patient with the chief complaint of acute progressive abdominal pain. Endoscopic findings of the small intestine were chronic and similar to those of polyangiitis (eosinophilic granulomatosis with polyangiitis). This case shows the presence of various clinical courses of EGE and the discrepancy between the symptoms and endoscopic appearance of vasculitis. Physicians should focus not only on acute symptoms but also on chronic phases of the disease to prevent disease progression and modify patients' help-seeking behaviors according to their symptoms.

摘要

嗜酸性粒细胞性胃肠炎(EGE)是一种累及胃肠道的疾病,其特征为嗜酸性粒细胞侵入胃肠道管腔。嗜酸性粒细胞的侵入会导致肠壁水肿和炎症,进而引发急性或慢性腹泻及腹痛。EGE可导致小肠慢性炎症,从而类似慢性血管炎。我们报告一例以急性进行性腹痛为主诉的24岁男性患者。小肠内镜检查结果为慢性,与多血管炎(嗜酸性肉芽肿性多血管炎)相似。该病例显示了EGE存在多种临床病程,以及血管炎症状与内镜表现之间的差异。医生不仅应关注急性症状,还应关注疾病的慢性阶段,以防止疾病进展,并根据患者症状调整其就医行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/84736b48abcc/cureus-0014-00000029813-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/780afbae799f/cureus-0014-00000029813-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/3729dd0a672a/cureus-0014-00000029813-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/84736b48abcc/cureus-0014-00000029813-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/780afbae799f/cureus-0014-00000029813-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/3729dd0a672a/cureus-0014-00000029813-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5216/9621689/84736b48abcc/cureus-0014-00000029813-i03.jpg

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ANCA-associated vasculitis.抗中性粒细胞胞浆抗体相关性血管炎。
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