Wang Sicheng, Tian Chuanxi, Gao Zezheng, Zhang Boxun, Zhao Linhua
Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Front Cardiovasc Med. 2022 Oct 20;9:1018841. doi: 10.3389/fcvm.2022.1018841. eCollection 2022.
Diabetic cardiomyopathy is one of the most life-threatening diabetic complications. However, the previous studies only discuss a particular aspect or characteristic of DCM, the current state and trends were explored by limited research. We aimed to perform a systemically bibliometric study of DCM research progress status in the past decade, visualize the internal conceptual structure and potential associations, and further explore the prospective study trends.
Articles related to DCM published from January 2012 to December 2021 were collected in the Web of Science core collection (WoSCC) database on June 24, 2022. We exported all bibliographic records, including titles, abstracts, keywords, authorship, institutions, addresses, publishing sources, references, citation times, and year of publication. In addition, the journal Impact Factor and Hirsch index were obtained from the Journal Citation Report. We conducted the data screening, statistical analysis, and visualization the Bibliometrix R package. VOS viewer software was employed to generate the collaboration network map among countries and institutions for better performance in visualization.
In total, 1,887 original research articles from 2012 to 2021 were identified. The number of annual publications rapidly increased from 107 to 278, and a drastic increase in citation times was observed in 2017-2019. As for global contributions, the United States was the most influential country with the highest international collaboration, while China was the most productive country. Professor Cai Lu was the most prolific author. Shandong University published the most articles. journal released the most DCM-related articles. "Metabolic Stress-induced Activation of FoxO1 Triggers Diabetic Cardiomyopathy in Mice" Battiprolu PK et al., J Clin Invest, 2012. was the most top-cited article regarding local citations. The top three keywords in terms of frequency were apoptosis, oxidative stress, and fibrosis. The analysis of future topic trends indicated that "Forkhead box protein O1," "Heart failure with preserved ejection fraction," "Dapagliflozin," "Thioredoxin," "Mitochondria dysfunction," "Glucose," "Pyroptosis," "Cardiac fibroblast" and "Long non-coding RNA" could be promising hotspots.
This study provides meaningful insights into DCM, which is expected to assist cardiologists and endocrinologists in exploring frontiers and future research directions in the domain through a refined and concise summary.
糖尿病心肌病是最危及生命的糖尿病并发症之一。然而，以往的研究仅讨论了糖尿病心肌病的某个特定方面或特征，目前的研究现状和趋势尚未得到充分探讨。我们旨在对过去十年糖尿病心肌病的研究进展进行系统的文献计量学研究，可视化其内部概念结构和潜在关联，并进一步探索未来的研究趋势。
2022年6月24日，在科学网核心合集（WoSCC）数据库中收集了2012年1月至2021年12月期间发表的与糖尿病心肌病相关的文章。我们导出了所有的文献记录，包括标题、摘要、关键词、作者、机构、地址、出版来源、参考文献、被引次数和发表年份。此外，期刊影响因子和Hirsch指数来自期刊引证报告。我们使用Bibliometrix R包进行数据筛选、统计分析和可视化。使用VOS viewer软件生成国家和机构之间的合作网络图，以获得更好的可视化效果。
共确定了2012年至2021年期间的1887篇原创研究文章。年发表量从107篇迅速增加到278篇，2017 - 2019年被引次数急剧增加。在全球贡献方面，美国是最具影响力的国家，国际合作度最高，而中国是发文量最多的国家。蔡璐教授是发文量最多的作者。山东大学发表的文章最多。某期刊发表的糖尿病心肌病相关文章最多。“代谢应激诱导的FoxO1激活触发小鼠糖尿病心肌病”（Battiprolu PK等人，《临床研究杂志》，2012年）是被引次数最多的本地引用文章。出现频率最高的前三个关键词是细胞凋亡、氧化应激和纤维化。未来主题趋势分析表明，“叉头框蛋白O1”、“射血分数保留的心力衰竭”、“达格列净”、“硫氧还蛋白”、“线粒体功能障碍”、“葡萄糖”、“细胞焦亡”、“心脏成纤维细胞”和“长链非编码RNA”可能是有前景的热点。
本研究为糖尿病心肌病提供了有意义的见解，有望通过精炼简洁的总结，帮助心脏病学家和内分泌学家探索该领域的前沿和未来研究方向。
