Papiha S S, Rodger R S
Hum Genet. 1986 Mar;72(3):260-1. doi: 10.1007/BF00291891.
C3 and BF allele frequencies were studied in 55 patients with idiopathic membranous nephropathy (IMN) and unrelated normal individuals from North-East England. Eighteen of these IMN patients progressed to renal failure and C3*S allele showed a significant increase in these patients. A possible mechanism for this increase is briefly discussed.
对来自英格兰东北部的55例特发性膜性肾病(IMN)患者及无关正常个体的C3和BF等位基因频率进行了研究。其中18例IMN患者进展为肾衰竭,C3*S等位基因在这些患者中显著增加。本文简要讨论了这种增加的可能机制。