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无肝胆疾病情况下由肺炎克雷伯菌引起的肝脓肿

Liver Abscess Caused by Klebsiella Pneumoniae in the Absence of Hepatobiliary Disease.

作者信息

Ibrahim Saira, Nallapaneni Naga Neelima, Muthulingam Dharushana

机构信息

Internal Medicine, SSM Health St. Mary's Hospital, St. Louis, USA.

Infectious Disease, St. Louis ID PC, St. Louis, USA.

出版信息

Cureus. 2022 Sep 30;14(9):e29789. doi: 10.7759/cureus.29789. eCollection 2022 Sep.

DOI:10.7759/cureus.29789
PMID:36340565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9618281/
Abstract

is notorious for causing abscesses in patients without any previous hepatobiliary disease and is a cause of liver abscesses. We report the case of a 70-year-old man with a past medical history of hypertension and benign prostatic hyperplasia who presented with a cough and fever lasting two weeks. The findings from his physical examination were unremarkable, but his laboratory investigations were significant for elevated inflammatory markers. A computed tomography scan of his abdomen revealed a complex septated cyst in the right lobe of his liver, and his blood culture was positive for . He responded well to drainage and intravenous and oral antibiotics. His abscess resolved fully. Cases of in the United States are rare, and studies are necessary to explore its epidemiology. Atypical symptoms make diagnosis a challenge, and physicians are urged to retain high levels of suspicion to diagnose and treat such cases early.

摘要

在没有任何既往肝胆疾病的患者中,它因导致脓肿而声名狼藉,是肝脓肿的一个病因。我们报告一例70岁男性病例,他有高血压和良性前列腺增生的既往病史,出现咳嗽和发热持续两周。体格检查结果无异常,但实验室检查显示炎症标志物升高。腹部计算机断层扫描显示其肝脏右叶有一个复杂的分隔囊肿,血液培养对……呈阳性。他对引流以及静脉和口服抗生素反应良好。他的脓肿完全消退。在美国,……病例很少见,有必要开展研究以探索其流行病学。非典型症状使诊断成为一项挑战,敦促医生保持高度怀疑以早期诊断和治疗此类病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/6ea3034c02a1/cureus-0014-00000029789-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/d52ac0cd5836/cureus-0014-00000029789-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/396d10a1c034/cureus-0014-00000029789-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/6ea3034c02a1/cureus-0014-00000029789-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/d52ac0cd5836/cureus-0014-00000029789-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/396d10a1c034/cureus-0014-00000029789-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cab/9618281/6ea3034c02a1/cureus-0014-00000029789-i03.jpg

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Clin Infect Dis. 2020 Aug 14;71(4):952-959. doi: 10.1093/cid/ciz881.
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Liver Abscess.肝脓肿
Infect Chemother. 2018 Sep;50(3):210-218. doi: 10.3947/ic.2018.50.3.210.
3
Klebsiella Pneumoniae Liver Abscess: a Case Report and Review of Literature.肺炎克雷伯菌肝脓肿:一例报告及文献综述
Cureus. 2017 Jan 10;9(1):e970. doi: 10.7759/cureus.970.
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Klebsiella pneumoniae Liver Abscess: An Emerging Disease.肺炎克雷伯菌肝脓肿:一种新兴疾病。
Am J Med Sci. 2016 Mar;351(3):297-304. doi: 10.1016/j.amjms.2015.12.018.
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Community-acquired Klebsiella pneumoniae liver abscess: an emerging infection in Ireland and Europe.社区获得性肺炎克雷伯菌肝脓肿:爱尔兰和欧洲的一种新出现的感染。
Infection. 2013 Jun;41(3):681-6. doi: 10.1007/s15010-013-0408-0. Epub 2013 Feb 5.
6
Higher rate of colorectal cancer among patients with pyogenic liver abscess with Klebsiella pneumoniae than those without: an 11-year follow-up study.化脓性肝脓肿合并肺炎克雷伯菌感染的患者比未合并肺炎克雷伯菌感染的患者结直肠癌发病率更高:一项为期 11 年的随访研究。
Colorectal Dis. 2012 Dec;14(12):e794-801. doi: 10.1111/j.1463-1318.2012.03174.x.
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