Department of Pathology, Keck School of Medicine, University of Southern California; Department of Urology, Keck School of Medicine, University of Southern California.
Department of Anatomic and Clinical Pathology, Tufts University School of Medicine and Tufts Medical Center, 800 Washington St., Box 802, Boston, MA 02111.
Surg Pathol Clin. 2022 Dec;15(4):661-679. doi: 10.1016/j.path.2022.08.003. Epub 2022 Oct 13.
Staging and reporting of cancers of the urinary tract have undergone major changes in the past decade to meet the needs for improved patient management. Substantial progress has been made. There, however, remain issues that require further clarity, including the substaging of pT1 tumors, grading and reporting of tumors with grade heterogeneity, and following NAC. Multi-institutional collaborative studies with prospective data will further inform the accurate diagnosis, staging, and reporting of these tumors, and in conjunction with genomic data will ultimately contribute to precision and personalized patient management.
在过去的十年中,为了满足改善患者管理的需求,泌尿系统癌症的分期和报告已经发生了重大变化。已经取得了重大进展。然而,仍有一些问题需要进一步明确,包括 pT1 肿瘤的亚分期、分级和报告具有分级异质性的肿瘤,以及新辅助化疗后的报告。多机构合作的前瞻性研究将进一步为这些肿瘤的准确诊断、分期和报告提供信息,并与基因组数据一起最终有助于精准和个性化的患者管理。