小鼠内毒素血症和肾上腺素高反应性死亡
Endotoxemia and adrenaline-hyperreactive death in mice.
作者信息
Kuratsuka K, Shimazaki Y, Funasaka I, Watabe Y
出版信息
Experientia. 1978 Nov 15;34(11):1483-4. doi: 10.1007/BF01932367.
PMID:363443
Abstract
Mice given i.v. a sublethal dose of endotoxin in advance died with shock-like symptoms on administration of sublethal adrenaline dose. The lethal adrenaline-hyperreaction induced by endotoxin appeared gradually within a few h, showed maximum response after several h and almost disappeared 24 h after endotoxin administration.
摘要
预先静脉注射亚致死剂量内毒素的小鼠，在给予亚致死剂量肾上腺素时会出现类似休克的症状而死亡。内毒素诱导的致死性肾上腺素高反应在数小时内逐渐出现，数小时后出现最大反应，在内毒素注射24小时后几乎消失。
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