St James's Hospital, Dublin, Ireland.
Anaesthesiol Intensive Ther. 2022;54(4):310-314. doi: 10.5114/ait.2022.120741.
Upper gastrointestinal bleeding (UGIB) is a common reason for intensive care admission. While there exist a number of UGIB scoring systems which are used to predict mortality, there are limited studies assessing the discriminative value of these scores in intensive care unit (ICU) patients. The purpose of this study was to analyse five different UGIB scoring systems in predicting ICU mortality and length of stay and compare them to two commonly used ICU mortality scoring systems.
We retrospectively identified all patients requiring ICU admission for UGIB to St James's Hospital over an 18-month period. We calculated their AIM65, Glasgow- Blatchford score, pre- and post-Rockall score, ABC, APACHE II and SOFA scores. We used area under the receiver operating characteristic curve (AUROC) to compare the predictive values of these six scoring systems for ICU and hospital mortality as well as ICU length of stay greater than seven days.
APACHE II showed excellent discriminative value in predicting mortality in ICU patients (AUROC: 0.87; CI: 0.75-0.99) while the SOFA score showed good discriminative value (AUROC: 0.71; CI: 0.50-0.93). None of the UGIB scoring systems predicted mortality in these patients. All scoring systems showed poor discriminative value in predicting ICU length of stay.
We were not able to validate any of these UGIB scoring systems for mortality or length of stay prediction in ICU patients. This study supports the validity of APACHE II as a clinical tool for predicting mortality in ICU patients with UGIB.
上消化道出血(UGIB)是重症监护病房(ICU)收治的常见原因。虽然有许多用于预测死亡率的 UGIB 评分系统,但评估这些评分在 ICU 患者中的判别价值的研究有限。本研究旨在分析五种不同的 UGIB 评分系统在预测 ICU 死亡率和住院时间方面的作用,并将其与两种常用的 ICU 死亡率评分系统进行比较。
我们回顾性地确定了在 18 个月期间因 UGIB 需要入住 ICU 的所有 St James 医院患者。我们计算了他们的 AIM65、格拉斯哥-布拉奇福德评分、前和后 Rockall 评分、ABC、APACHE II 和 SOFA 评分。我们使用受试者工作特征曲线下面积(AUROC)来比较这六种评分系统对 ICU 和医院死亡率以及 ICU 住院时间超过七天的预测值。
APACHE II 在预测 ICU 患者死亡率方面具有出色的判别价值(AUROC:0.87;CI:0.75-0.99),而 SOFA 评分具有良好的判别价值(AUROC:0.71;CI:0.50-0.93)。这些患者的任何 UGIB 评分系统均无法预测死亡率。所有评分系统在预测 ICU 住院时间方面的判别价值均较差。
我们无法验证这些 UGIB 评分系统在 ICU 患者中的死亡率或住院时间预测中的有效性。这项研究支持 APACHE II 作为预测 ICU 患者 UGIB 死亡率的临床工具的有效性。