O'Donovan Gary, Lee I-Min, Hamer Mark, García-Garro Patricia, Duran-Aniotz Claudia, Ibáñez Agustín, Sarmiento Olga L, Hessel Philipp
Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile.
Facultad de Medicina, Universidad de los Andes, Bogotá, Colombia.
Eur Rev Aging Phys Act. 2022 Nov 9;19(1):28. doi: 10.1186/s11556-022-00307-y.
Mild cognitive impairment often precedes dementia. The purpose of this analysis was to estimate the population attributable fraction for physical activity in Colombia, which is the reduction in cases that would occur if all participants were physically active.
The sample included 20,174 men and women aged 70.04 ± 7.68 years (mean ± SD) from the National Survey of Health, Wellbeing and Ageing. Trained interviewers administered a shorter version of the mini-mental state examination and mild cognitive impairment was defined as a score of 12 or less out of 19. Logistic regression models were fitted and population attributable fractions for physical activity were calculated. All analyses were adjusted for age, sex, height, education, income, civil status, smoking, and alcohol drinking.
The prevalence of physical activity was approximately 50% when defined as walking between 9 and 20 blocks at least three times per week. Theoretically, 19% of cases of mild cognitive impairment would be eliminated if all adults were to walk (95% confidence interval: 16%, 22%). The prevalence was approximately 20% when defined as taking part in vigorous sport or exercise at least three times per week. Theoretically, 23% of cases of mild cognitive impairment would be eliminated if all adults were to take part in vigorous sport or exercise (16%, 30%). Similar results were observed after removing those who reported mental health problems.
Physical activity, whether walking or vigorous sport and exercise, has the potential to substantially reduce the burden of mild cognitive impairment in Colombia.
轻度认知障碍往往先于痴呆症出现。本分析的目的是估计哥伦比亚身体活动的人群归因分数,即如果所有参与者都进行身体活动,将会减少的病例数。
样本包括来自全国健康、幸福与老龄化调查的20174名年龄在70.04±7.68岁(均值±标准差)的男性和女性。经过培训的访谈员进行简易精神状态检查表的简短版本测试,轻度认知障碍被定义为在19分中得分12分及以下。拟合逻辑回归模型并计算身体活动的人群归因分数。所有分析均针对年龄、性别、身高、教育程度、收入、婚姻状况、吸烟和饮酒情况进行了调整。
当身体活动定义为每周至少三次步行9至20个街区时,其患病率约为50%。理论上,如果所有成年人都步行,19%的轻度认知障碍病例将被消除(95%置信区间:16%,22%)。当身体活动定义为每周至少三次参加剧烈运动或锻炼时,患病率约为20%。理论上,如果所有成年人都参加剧烈运动或锻炼,23%的轻度认知障碍病例将被消除(16%,30%)。在排除那些报告有心理健康问题的人之后,观察到了类似的结果。
无论是步行还是剧烈运动和锻炼,身体活动都有可能大幅减轻哥伦比亚轻度认知障碍的负担。