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气肿性膀胱炎:2型糖尿病控制不佳的致命并发症。

Emphysematous Cystitis: A Fatal Complication of Uncontrolled Type-2 Diabetes Mellitus.

作者信息

Raval Darshankumar M, Rathod Vaishnavi M, Patel Nilay S, Dobariya Riya, Sharma Bhavya

机构信息

Department of General Medicine, Sir Sayajirao General (SSG) Hospital and Medical College Baroda, Vadodara, IND.

出版信息

Cureus. 2022 Oct 7;14(10):e30028. doi: 10.7759/cureus.30028. eCollection 2022 Oct.

Abstract

Emphysematous cystitis (EC) is a rare type of complicated urinary tract infection mostly seen in elderly females with diabetes, characterized by gas within the bladder lumen and wall. The presenting symptoms are variable, ranging from no symptoms to severe sepsis. The commonly isolated organisms in urine cultures are and . Imaging studies, namely plain conventional abdominal radiography and computed tomography, are necessary to make a definitive diagnosis of EC. The management includes medical treatment with culture-guided antibiotics, whereas surgical intervention such as cystectomy is rarely required in severe cases. Here, we have a case of a 48-year-old diabetic female diagnosed with EC on radio imaging. The patient was aggressively treated with higher antibiotics such as piperacillin/tazobactam, clindamycin, and fosfomycin along with measures to control blood sugars. However, she developed severe sepsis and succumbed to death. Our report presents one of the rare cases of EC as a life-threatening complication in diabetics, suggesting that every case of urinary tract infection in uncontrolled diabetics should be thoroughly investigated and treated to prevent fatal complications.

摘要

气肿性膀胱炎(EC)是一种罕见的复杂性尿路感染类型,多见于老年糖尿病女性,其特征为膀胱腔和膀胱壁内出现气体。临床表现多样,从无症状到严重脓毒症不等。尿培养中常见的分离菌为 和 。影像学检查,即普通传统腹部X线摄影和计算机断层扫描,对于EC的明确诊断是必要的。治疗包括使用培养指导的抗生素进行药物治疗,而在严重病例中很少需要进行诸如膀胱切除术等手术干预。在此,我们有一例48岁的糖尿病女性患者,经影像学检查诊断为EC。该患者接受了哌拉西林/他唑巴坦、克林霉素和磷霉素等强效抗生素治疗以及控制血糖的措施。然而,她发展为严重脓毒症并死亡。我们的报告呈现了EC作为糖尿病患者危及生命的并发症的罕见病例之一,提示对于未控制的糖尿病患者的每一例尿路感染都应进行彻底调查和治疗,以预防致命并发症。

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