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气肿性膀胱炎与感染性休克:一种应对危及生命的泌尿系统感染的多学科方法

Emphysematous Cystitis and Septic Shock: A Multidisciplinary Approach to Managing a Life-Threatening Urological Infection.

作者信息

Frazão Teresa, Brito Ana Patrícia, Cerdeira Frazão Joana, Cotter Jorge

机构信息

Internal Medicine, Unidade Local de Saúde do Alto Ave, Guimarães, PRT.

Internal Medicine, Hospital Senhora da Oliveira, Guimarães, PRT.

出版信息

Cureus. 2024 Nov 14;16(11):e73685. doi: 10.7759/cureus.73685. eCollection 2024 Nov.

DOI:10.7759/cureus.73685
PMID:39677186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11645984/
Abstract

Emphysematous cystitis (EC) is a rare, life-threatening urinary tract infection (UTI) characterized by gas formation within the bladder wall and lumen. It predominantly occurs in patients with poorly controlled diabetes. We present a case of a 61-year-old male with poorly controlled diabetes and chronic alcoholism who was admitted in a comatose state due to severe septic shock secondary to EC. Initial management included mechanical ventilation, vasopressor support, and broad-spectrum antibiotics. Cultures revealed resistant to the initial therapy, prompting a switch to Meropenem. With prompt multidisciplinary intervention, the patient gradually recovered, was successfully extubated, and was transferred from the ICU by day 5. He was discharged from the hospital on day 17 with full clinical recovery. This case highlights the critical role of early diagnosis, appropriate antimicrobial therapy, and intensive supportive care in managing severe cases of EC with multiorgan failure.

摘要

气肿性膀胱炎(EC)是一种罕见的、危及生命的尿路感染(UTI),其特征是膀胱壁和腔内形成气体。它主要发生在糖尿病控制不佳的患者中。我们报告一例61岁男性病例,该患者糖尿病控制不佳且患有慢性酒精中毒,因气肿性膀胱炎继发严重感染性休克而昏迷入院。初始治疗包括机械通气、血管活性药物支持和广谱抗生素。培养结果显示对初始治疗耐药,促使改用美罗培南。通过及时的多学科干预,患者逐渐康复,成功脱机,并在第5天从重症监护病房转出。他于第17天临床完全康复出院。该病例突出了早期诊断、适当的抗菌治疗和强化支持治疗在管理伴有多器官功能衰竭的严重气肿性膀胱炎病例中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a707/11645984/37ea3bdd203e/cureus-0016-00000073685-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a707/11645984/37ea3bdd203e/cureus-0016-00000073685-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a707/11645984/37ea3bdd203e/cureus-0016-00000073685-i01.jpg

相似文献

1
Emphysematous Cystitis and Septic Shock: A Multidisciplinary Approach to Managing a Life-Threatening Urological Infection.气肿性膀胱炎与感染性休克:一种应对危及生命的泌尿系统感染的多学科方法
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本文引用的文献

1
Scoring Systems to Evaluate the Mortality Risk of Patients with Emphysematous Cystitis: A Retrospective Observational Study.评估气肿性膀胱炎患者死亡风险的评分系统:一项回顾性观察研究。
J Pers Med. 2023 Feb 13;13(2):318. doi: 10.3390/jpm13020318.
2
Emphysematous Cystitis: A Fatal Complication of Uncontrolled Type-2 Diabetes Mellitus.气肿性膀胱炎:2型糖尿病控制不佳的致命并发症。
Cureus. 2022 Oct 7;14(10):e30028. doi: 10.7759/cureus.30028. eCollection 2022 Oct.
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Emphysematous cystitis: a review of 135 cases.气肿性膀胱炎:135例病例回顾
BJU Int. 2007 Jul;100(1):17-20. doi: 10.1111/j.1464-410X.2007.06930.x. Epub 2007 May 17.
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Emphysematous cystitis: illustrative case report and review of the literature.气肿性膀胱炎:病例报告及文献复习
Medicine (Baltimore). 2007 Jan;86(1):47-53. doi: 10.1097/MD.0b013e3180307c3a.
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Emphysematous cystitis: an unusual disease of the Genito-Urinary system suspected on imaging.气肿性膀胱炎:一种在影像学上疑似的泌尿生殖系统罕见疾病。
Ann Clin Microbiol Antimicrob. 2004 Oct 5;3:20. doi: 10.1186/1476-0711-3-20.
6
Cystitis emphysematosa; 19 cases with intraluminal and interstitial collections of gas.气肿性膀胱炎;19例伴有腔内和间质气体积聚。
Am J Roentgenol Radium Ther Nucl Med. 1961 Nov;86:850-62.
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Emphysematous cystitis: a review of the spectrum of disease.气肿性膀胱炎:疾病谱综述
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