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乳腺癌筛查模式的挑战与变革

Challenges and Changes of the Breast Cancer Screening Paradigm.

作者信息

Cömert Didem, van Gils Carla H, Veldhuis Wouter B, Mann Ritse M

机构信息

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Radiology and Nuclear Medicine, Utrecht University Medical Center, Utrecht, The Netherlands.

出版信息

J Magn Reson Imaging. 2023 Mar;57(3):706-726. doi: 10.1002/jmri.28495. Epub 2022 Nov 9.

DOI:10.1002/jmri.28495
PMID:36349728
Abstract

Since four decades mammography is used for early breast cancer detection in asymptomatic women and still remains the gold standard imaging modality. However, population screening programs can be personalized and women can be divided into different groups based on risk factors and personal preferences. The availability of new and evolving imaging modalities, for example, digital breast tomosynthesis, dynamic-contrast-enhanced magnetic resonance imaging (MRI), abbreviated MRI protocols, diffusion-weighted MRI, and contrast-enhanced mammography leads to new challenges and perspectives regarding the feasibility and potential harms of breast cancer screening. The aim of this review is to discuss the current guidelines for different risk groups, to analyze the recent published studies about the diagnostic performance of the imaging modalities and to discuss new developments and future perspectives. LEVEL OF EVIDENCE: 1 TECHNICAL EFFICACY: Stage 6.

摘要

四十年来,乳腺钼靶一直用于无症状女性的早期乳腺癌检测,至今仍是金标准成像方式。然而,人群筛查项目可以个性化,女性可根据风险因素和个人偏好分为不同组。新型且不断发展的成像方式的出现,例如数字乳腺断层合成、动态对比增强磁共振成像(MRI)、简化MRI方案、扩散加权MRI和对比增强乳腺钼靶,给乳腺癌筛查的可行性和潜在危害带来了新的挑战和观点。本综述的目的是讨论针对不同风险组的当前指南,分析最近发表的关于成像方式诊断性能的研究,并讨论新进展和未来展望。证据级别:1 技术效能:6级

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