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肌肉骨骼栓塞疗法。

Musculoskeletal Embolotherapy.

机构信息

University Department of Radiology, Royal Berkshire NHS Foundation Trust, Reading, UK.

出版信息

Cardiovasc Intervent Radiol. 2023 Nov;46(11):1517-1524. doi: 10.1007/s00270-022-03302-z. Epub 2022 Nov 9.

DOI:10.1007/s00270-022-03302-z
PMID:36352126
Abstract

Painful articular musculoskeletal (MSK) conditions are common, debilitating and sometimes difficult to treat. Transcatheter embolisation may offer an alternative way to manage the pain associated with these conditions, but the field is still in its infancy. To date, the most commonly studied indication is knee osteoarthritis, but the technique has been trailed in multiple other tissue beds, including for adhesive capsulitis and tendinopathies. Whilst early results appear promising, the existing studies are mostly open-labelled and non-randomised; there is a need for high-quality evidence to robustly assess the procedures efficacy. In this review, we set out to evaluate the current evidence underlying the pathophysiology and mechanism of action of embolisation; discuss the technical aspects of the procedure including embolic selection, and appraise the published clinical outcomes and adverse effects. Finally, we discuss the future directions and research priorities in this rapidly developing field.

摘要

关节肌肉骨骼(MSK)疼痛性疾病较为常见,患者常感到虚弱,有时难以治疗。经导管栓塞可能为治疗这些疾病相关疼痛提供了一种替代方法,但该领域仍处于起步阶段。迄今为止,最常研究的适应证是膝骨关节炎,但该技术已在多个其他组织部位进行了试验,包括粘连性肩关节囊炎和肌腱病。尽管早期结果看起来很有希望,但现有的研究大多是开放标签和非随机的;需要高质量的证据来稳健地评估这些程序的疗效。在这篇综述中,我们旨在评估栓塞的病理生理学和作用机制的现有证据;讨论该手术的技术方面,包括栓塞剂的选择,并评估已发表的临床结果和不良反应。最后,我们讨论了这个快速发展领域的未来方向和研究重点。

相似文献

1
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Cardiovasc Intervent Radiol. 2023 Nov;46(11):1517-1524. doi: 10.1007/s00270-022-03302-z. Epub 2022 Nov 9.
2
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引用本文的文献

1
Mastering Musculoskeletal Interventions: CVIR's Newest Special Issue.掌握肌肉骨骼干预措施:CVIR最新特刊
Cardiovasc Intervent Radiol. 2023 Nov;46(11):1437-1438. doi: 10.1007/s00270-023-03586-9. Epub 2023 Oct 24.
2
Commentary: Intra-arterial Injection of Temporary Embolic Material Through a Needle Inserted into the Radial or Ulnar Artery for Distal and Proximal Interphalangeal Joint Osteoarthritis: A Retrospective Study of 92 Patients.评论:通过插入桡动脉或尺动脉的针进行动脉内注射临时栓塞材料治疗远侧和近侧指间关节骨关节炎:92例患者的回顾性研究
Cardiovasc Intervent Radiol. 2023 Oct;46(10):1383-1384. doi: 10.1007/s00270-023-03553-4. Epub 2023 Sep 19.

本文引用的文献

1
A Review of Musculoskeletal Embolization to Treat Pain Outside of the Knee.肌肉骨骼栓塞术治疗膝关节外疼痛的综述
Semin Intervent Radiol. 2021 Nov 24;38(5):515-517. doi: 10.1055/s-0041-1736530. eCollection 2021 Dec.
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Transarterial Embolization for the Treatment of Chronic Musculoskeletal Pain: A Systematic Review of Indications, Safety, and Efficacy.经动脉栓塞治疗慢性肌肉骨骼疼痛:适应证、安全性及疗效的系统评价
ACR Open Rheumatol. 2022 Mar;4(3):209-217. doi: 10.1002/acr2.11383. Epub 2021 Nov 29.
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Results from a United States Investigational Device Study of Adhesive Capsulitis Embolization in the Treatment of Shoulder Pain: The Adhesive Capsulitis Embolization Study.
美国一项关于粘连性肩关节囊炎栓塞治疗肩痛的研究结果:粘连性肩关节囊炎栓塞研究。
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4
Transcatheter Arterial Embolization Using Imipenem/Cilastatin Sodium for Chronic Low Back Pain Resistant to Conservative Treatment: A Pilot Study with 2-Year Follow-Up.经保守治疗无效的慢性腰痛患者采用亚胺培南/西司他丁钠经导管动脉栓塞治疗:一项为期 2 年随访的初步研究。
Cardiovasc Intervent Radiol. 2021 Dec;44(12):1964-1970. doi: 10.1007/s00270-021-02976-1. Epub 2021 Oct 19.
5
Cadaveric and Angiographic Anatomical Considerations in the Genicular Arterial System: Implications for Genicular Artery Embolisation in Patients with Knee Osteoarthritis.关节动脉系统的尸体和血管解剖学考虑因素:对膝骨关节炎患者进行关节动脉栓塞的影响。
Cardiovasc Intervent Radiol. 2022 Jan;45(1):80-90. doi: 10.1007/s00270-021-02978-z. Epub 2021 Oct 17.
6
Multicenter Randomized Sham Controlled Study of Genicular Artery Embolization for Knee Pain Secondary to Osteoarthritis.多中心随机假手术对照研究:膝关节炎性膝痛的关节内动脉栓塞治疗。
J Vasc Interv Radiol. 2022 Jan;33(1):2-10.e2. doi: 10.1016/j.jvir.2021.09.019. Epub 2021 Oct 2.
7
Current Status of Trans-Arterial Embolization in Pain Management of Musculoskeletal Inflammatory Conditions - An Evidence-Based Review.经动脉栓塞术在肌肉骨骼炎症性疾病疼痛管理中的应用现状——基于证据的综述。
Cardiovasc Intervent Radiol. 2021 Nov;44(11):1699-1708. doi: 10.1007/s00270-021-02948-5. Epub 2021 Sep 2.
8
Osteoarthritis-Related Knee Pain Treated With Genicular Artery Embolization: A Systematic Review and Meta-analysis.膝下动脉栓塞治疗骨关节炎相关膝关节疼痛:一项系统评价和荟萃分析
Orthop J Sports Med. 2021 Jul 14;9(7):23259671211021356. doi: 10.1177/23259671211021356. eCollection 2021 Jul.
9
Intra-Arterial Infusion of Imipenem/Cilastatin Sodium through a Needle Inserted into the Radial Artery as a New Treatment for Refractory Trapeziometacarpal Osteoarthritis.经桡动脉置入针注入亚胺培南/西司他丁钠治疗难治性腕掌关节炎。
J Vasc Interv Radiol. 2021 Sep;32(9):1341-1347. doi: 10.1016/j.jvir.2021.06.024. Epub 2021 Jul 6.
10
Contrast-Enhanced Ultrasonography During Genicular Artery Embolization.膝关节动脉栓塞术中的超声造影检查
Cardiovasc Intervent Radiol. 2021 Nov;44(11):1830-1832. doi: 10.1007/s00270-021-02864-8. Epub 2021 May 12.