University Department of Radiology, Royal Berkshire NHS Foundation Trust, Reading, UK.
Cardiovasc Intervent Radiol. 2023 Nov;46(11):1517-1524. doi: 10.1007/s00270-022-03302-z. Epub 2022 Nov 9.
Painful articular musculoskeletal (MSK) conditions are common, debilitating and sometimes difficult to treat. Transcatheter embolisation may offer an alternative way to manage the pain associated with these conditions, but the field is still in its infancy. To date, the most commonly studied indication is knee osteoarthritis, but the technique has been trailed in multiple other tissue beds, including for adhesive capsulitis and tendinopathies. Whilst early results appear promising, the existing studies are mostly open-labelled and non-randomised; there is a need for high-quality evidence to robustly assess the procedures efficacy. In this review, we set out to evaluate the current evidence underlying the pathophysiology and mechanism of action of embolisation; discuss the technical aspects of the procedure including embolic selection, and appraise the published clinical outcomes and adverse effects. Finally, we discuss the future directions and research priorities in this rapidly developing field.
关节肌肉骨骼(MSK)疼痛性疾病较为常见,患者常感到虚弱,有时难以治疗。经导管栓塞可能为治疗这些疾病相关疼痛提供了一种替代方法,但该领域仍处于起步阶段。迄今为止,最常研究的适应证是膝骨关节炎,但该技术已在多个其他组织部位进行了试验,包括粘连性肩关节囊炎和肌腱病。尽管早期结果看起来很有希望,但现有的研究大多是开放标签和非随机的;需要高质量的证据来稳健地评估这些程序的疗效。在这篇综述中,我们旨在评估栓塞的病理生理学和作用机制的现有证据;讨论该手术的技术方面,包括栓塞剂的选择,并评估已发表的临床结果和不良反应。最后,我们讨论了这个快速发展领域的未来方向和研究重点。