Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
Computer Simulation and Advanced Research Technologies (CSART), Sydney, Australia.
BMC Psychiatry. 2022 Nov 9;22(1):692. doi: 10.1186/s12888-022-04352-w.
Multiple studies indicate that the prevalence of mental disorders in high-income countries has remained stable or increased despite substantial increases in the provision of care, leading some authors to question the effectiveness of increasing access to current treatments as a means of improving population mental health.
We developed a system dynamics model of mental disorder incidence and treatment-dependent recovery to assess two potential explanations for the apparent failure of increasing treatment provision to reduce mental disorder prevalence: 1) an increase in the individual-level risk of disorder onset; and 2) declining effectiveness of care resulting from insufficient services capacity growth. Bayesian Markov Chain Monte Carlo (MCMC) methods were used to fit the model to data on the prevalence of high to very high psychological distress in Australia for the period 2008-2019.
Estimates of yearly rates of increase in the per capita incidence of high to very high psychological distress and the proportion of patients recovering when treated indicate that the individual-level risk of developing high to very high levels of distress increased between 2008 and 2019 (posterior probability > 0.999) but provide no evidence for declining treatment effectiveness. Simulation analyses suggest that the prevalence of high to very high psychological distress would have decreased from 14.4% in 2008 to 13.6% in 2019 if per capita incidence had not increased over this period (prevalence difference 0.0079, 95% credible interval 0.0015-0.0176).
Our analyses indicate that a modest but significant effect of increasing access to mental health care in Australia between 2008 and 2019 was obscured by a concurrent increase in the incidence of high to very high psychological distress.
多项研究表明,尽管提供的护理服务大幅增加,但高收入国家的精神障碍患病率保持稳定或有所上升,这使得一些作者质疑增加现有治疗方法的可及性作为改善人群心理健康的手段是否有效。
我们开发了一个精神障碍发病率和治疗相关康复的系统动力学模型,以评估增加治疗提供以降低精神障碍患病率的明显失败的两个潜在解释:1)个体发病风险增加;2)由于服务能力增长不足导致护理效果下降。贝叶斯马尔可夫链蒙特卡罗(MCMC)方法用于拟合该模型,以拟合澳大利亚 2008-2019 年期间高至极高心理困扰流行率的数据。
高至极高心理困扰的人均发病率和治疗后康复患者比例的年增长率估计表明,2008 年至 2019 年间,个体发生高至极高水平困扰的风险增加(后验概率>0.999),但没有证据表明治疗效果下降。模拟分析表明,如果在此期间人均发病率没有增加,高至极高心理困扰的流行率将从 2008 年的 14.4%下降到 2019 年的 13.6%(流行率差异 0.0079,95%可信区间 0.0015-0.0176)。
我们的分析表明,2008 年至 2019 年期间澳大利亚心理健康服务可及性的适度但显著增加被高至极高心理困扰发病率的同时增加所掩盖。