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一项关于妊娠合并心脏病的母胎结局的研究。

A study on foetomaternal outcome of pregnancies complicated by cardiac diseases.

作者信息

Pillai Sheila Kamalasan, Monisha Subbaiya

机构信息

Department of OBGYN, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2022 Aug;11(8):4655-4660. doi: 10.4103/jfmpc.jfmpc_2402_21. Epub 2022 Aug 30.

DOI:10.4103/jfmpc.jfmpc_2402_21
PMID:36352940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9638560/
Abstract

UNLABELLED

Cardiac disease complicates around 1-4% of all pregnancies. This study has been conducted to know the incidence of cardiac diseases complicating pregnancy in our institution and to identify the spectrum of various cardiac diseases and their associated maternal and fetal complications.

OBJECTIVES OF THE STUDY

  1. To evaluate the maternal and fetal outcome in patients with cardiac disease in pregnancy. 2. To identify any significant association between the modified World Health Organisation (WHO) risk classification of maternal cardiovascular diseases and the maternal and fetal outcomes.

METHODS

This study was conducted in the Department of Obstetrics and Gynecology at Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil nadu.

STUDY DESIGN

Retrospective and Prospective observational study.

STUDY PERIOD

April 2017-April 2020. Sample Size 72 patients satisfying the inclusion criteria admitted from April 2017 to April 2020.

INCLUSION CRITERIA

Rheumatic heart disease, congenital heart disease, arrhythmias, and conduction disorders.

EXCLUSION CRITERIA

Cardiomyopathy.

RESULTS

The incidence of heart disease complicating pregnancy in our study was 0.5%. The ratio of RHD: CHD in our study was 4:1. There was no statistically significant association between the modified WHO risk classification of heart disease and the mode of delivery. 36.1% patients of the study group developed complications related to their cardiac disease, of which 96.3% belonged to the rheumatic heart disease (RHD) group. There were no cases of maternal mortality or perinatal mortality in our study.

CONCLUSIONS

According to our study, there was a statistically significant association between the maternal complications, namely. congestive cardiac failure and acute pulmonary edema and the modified WHO risk assessment class of maternal cardiovascular diseases in pregnancy. There was no statistically significant association between the perinatal morbidity and the modified WHO risk assessment class of maternal cardiovascular disease in pregnancy.

摘要

未标注

心脏病使约1%-4%的妊娠复杂化。本研究旨在了解我院妊娠合并心脏病的发病率,确定各种心脏病的范围及其相关的母婴并发症。

研究目的

  1. 评估妊娠合并心脏病患者的母婴结局。2. 确定改良世界卫生组织(WHO)孕产妇心血管疾病风险分类与母婴结局之间是否存在显著关联。

方法

本研究在泰米尔纳德邦金奈市斯里兰卡拉马钱德拉高等教育与研究学院妇产科进行。

研究设计

回顾性和前瞻性观察性研究。

研究期间

2017年4月至2020年4月。样本量为2017年4月至2020年4月收治的72例符合纳入标准的患者。

纳入标准

风湿性心脏病、先天性心脏病、心律失常和传导障碍。

排除标准

心肌病。

结果

本研究中妊娠合并心脏病的发病率为0.5%。本研究中风湿性心脏病与先天性心脏病的比例为4:1。心脏病的改良WHO风险分类与分娩方式之间无统计学显著关联。研究组36.1%的患者出现与心脏病相关的并发症,其中96.3%属于风湿性心脏病(RHD)组。本研究中无孕产妇死亡或围产期死亡病例。

结论

根据我们的研究,孕产妇并发症即充血性心力衰竭和急性肺水肿与妊娠期间孕产妇心血管疾病的改良WHO风险评估类别之间存在统计学显著关联。围产期发病率与妊娠期间孕产妇心血管疾病的改良WHO风险评估类别之间无统计学显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ada/9638560/3620a465c780/JFMPC-11-4655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ada/9638560/28dc6d88a10c/JFMPC-11-4655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ada/9638560/3620a465c780/JFMPC-11-4655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ada/9638560/28dc6d88a10c/JFMPC-11-4655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ada/9638560/3620a465c780/JFMPC-11-4655-g002.jpg

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Validation of modified World Health Organization classification for pregnant women with heart disease in a tertiary care center in southern Thailand.泰国南部一家三级医疗中心对心脏病孕妇采用的改良世界卫生组织分类法的验证。
Int J Womens Health. 2018 Jan 18;10:47-53. doi: 10.2147/IJWH.S150767. eCollection 2018.
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High-Risk Cardiac Disease in Pregnancy: Part I.妊娠期高危心脏病:第一部分。
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Pregnancy complicated by maternal heart disease: a review of 281 women.
妊娠合并心脏病:281例孕妇回顾性研究
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