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妊娠合并心脏病:281例孕妇回顾性研究

Pregnancy complicated by maternal heart disease: a review of 281 women.

作者信息

Konar Hiralal, Chaudhuri Snehamay

机构信息

Department of Obstetrics & Gynaecology, Midnapore Medical College & Hospital, CD 55, Salt Lake City, Kolkata, 700 064 India.

出版信息

J Obstet Gynaecol India. 2012 Jun;62(3):301-6. doi: 10.1007/s13224-012-0220-2. Epub 2012 Aug 17.

Abstract

OBJECTIVES

To study maternal heart disease in an Indian setting for: (1) different etiological factors, (2) different types of lesions, and (3) maternal and perinatal outcome.

METHODS

281 women with heart disease who delivered ≥28 weeks of gestation at different teaching institutions (tertiary care centres) in India were studied.

RESULTS

Rheumatic heart disease (n = 195; 69.4 %) with isolated mitral stenosis (n = 75; 26.7 %) were the commonest. Septal defect (n = 27; 9.6 %) was the predominant lesion among the congenital heart disease (n = 60; 21.3 %) patients, whereas in the miscellaneous group (n = 26; 9.2 %), ischemic heart disease (n = 10; 3.6 %) was the leading cause. Multiple cardiac lesions were also diagnosed in 100 (35.58 %) women. In 87 (31 %) women, diagnosis was made first time in labor. Majority n = 131, (46.6 %) had spontaneous vaginal delivery and few (n = 9; 3.3 %) required induction of labor. Cardiac complications were noted in 72 women (25.6 %). There were three (1.06 %) maternal deaths and perinatal mortality was 4 % (n = 11).

CONCLUSION

In this study, rheumatic heart disease in pregnancy is still predominant though acquired cardiac lesions are rising. In rheumatic heart disease, mitral valve involvement was the commonest and multiple valve lesions were a major observation. Most common obstetric complication was small for gestation baby. Maternal morbidities in the unbooked women are high and congestive cardiac failure was the major cardiac complication.

摘要

目的

在印度环境下研究孕产妇心脏病,包括:(1)不同病因因素;(2)不同类型病变;(3)孕产妇和围产期结局。

方法

对印度不同教学机构(三级医疗中心)中妊娠≥28周分娩的281例心脏病妇女进行了研究。

结果

风湿性心脏病(n = 195;69.4%),其中单纯二尖瓣狭窄(n = 75;26.7%)最为常见。房间隔缺损(n = 27;9.6%)是先天性心脏病(n = 60;21.3%)患者中的主要病变,而在其他组(n = 26;9.2%)中,缺血性心脏病(n = 10;3.6%)是主要病因。100例(35.58%)妇女还被诊断出有多种心脏病变。87例(31%)妇女在分娩时首次确诊。大多数(n = 131,46.6%)为自然阴道分娩,少数(n = 9;3.3%)需要引产。72例妇女(25.6%)出现心脏并发症。有3例(1.06%)孕产妇死亡,围产儿死亡率为4%(n = 11)。

结论

在本研究中,尽管后天性心脏病变呈上升趋势,但妊娠合并风湿性心脏病仍然占主导地位。在风湿性心脏病中,二尖瓣受累最为常见,多瓣膜病变是主要观察结果。最常见的产科并发症是小于胎龄儿。未登记产妇的孕产妇发病率较高,充血性心力衰竭是主要的心脏并发症。

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