Hygeia Hospital, 4 Erythrou Stavrou Str, 15123, Athens, Greece.
Johns Hopkins Hospital, Baltimore, MD, USA.
J Interv Card Electrophysiol. 2023 Jun;66(4):991-996. doi: 10.1007/s10840-022-01408-5. Epub 2022 Nov 10.
Mathematical modelling has allowed calculation of the length of the slow and fast pathways in typical atrioventricular nodal reentrant tachycardia (AVNRT). The length of the slow pathway has been correlated with the measured length of the right inferior extension in human histologic specimens, but no histology data exist about the fast pathway.
In preparations of cadaveric human hearts, the AV node was identified, and the site of the fast pathway was projected according to both existing evidence and results of our electroanatomic mapping. This permitted measurement of the length of the fast pathway as a limb of the tachycardia circuit.
Measurements of the length of the projected area of the fast pathway on histology specimens were performed in 8 hearts. The estimated length of the fast pathway was 39.6 ± 5.8 mm (range: 30.4-45.9 mm). These numbers are comparable to those produced by mathematical calculations of the length of the fast pathway.
Typical AVNRT uses a circuit from the AV node to the septal isthmus of an average size of 5-6 cm, confined within the pyramid of Koch.
数学建模允许计算典型房室结折返性心动过速（AVNRT）中慢径和快径的长度。慢径的长度与人类组织学标本中测量的右后下延伸长度相关，但尚无关于快径的组织学数据。
在尸体人心的标本中，确定房室结的位置，并根据现有证据和我们的电解剖标测结果，预测快径的位置。这允许测量心动过速回路中快径的长度。
在 8 个心脏标本中进行了对快径投射区域的组织学长度测量。估计的快径长度为 39.6 ± 5.8 毫米（范围：30.4-45.9 毫米）。这些数值与快径长度的数学计算结果相当。
典型的房室结折返性心动过速使用一个从房室结到平均大小为 5-6 厘米的间隔峡部的回路，该回路局限于 Koch 三角内。
