College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Research & Innovation Centre, King Saud Medical City, Ministry of Health Riyadh, Riyadh, Saudi Arabia.
J Epidemiol Glob Health. 2022 Dec;12(4):548-551. doi: 10.1007/s44197-022-00075-z. Epub 2022 Nov 10.
The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analyzed. Descriptive, univariate, and multivariate logistic regression analyses were carried out. Out of the 206 studied patients, 28 died. Hypertension, cardiac disease, and hospital admission were predictors of death in univariate and multivariate logistic regression analysis. Moreover, age was a significant predictor of death, while increased BMI seemed to be protective at an older age. Therefore, a new score was suggested taking into consideration both factors, namely age/BMI score. Although older age was associated with death in univariate (OR, 1.09 [95% CI 1.05-1.12], p < 0.001) and multivariate analysis (OR, 1.05 [95% CI 1.02-1.09], p = 0.004), a higher age/BMI score was a stronger predictor of death than age alone, in both univariate (OR 4.42 [95% CI 2.50-7.80], p < 0.001) and multivariate analysis (OR 3.11 [95% CI 1.66-5.82], p < 0.001). Several factors appear to contribute to the risk of COVID-19 death. Interestingly, our new age/BMI score seems to carry a higher risk of death than age alone. This new score will be designated as the Hajeer score. Since this is a small cohort study, we recommend investigating this score in a larger cohort.
本研究旨在探讨年龄和 BMI 对 2019 年冠状病毒病（COVID-19）患者死亡风险的影响。本研究纳入了 206 例沙特 COVID-19 患者。收集并分析了年龄、BMI、住院、合并症和死亡的数据。进行了描述性、单变量和多变量逻辑回归分析。在 206 例研究患者中，有 28 例死亡。高血压、心脏病和住院是单变量和多变量逻辑回归分析中死亡的预测因素。此外，年龄是死亡的显著预测因素，而随着年龄的增长，BMI 增加似乎具有保护作用。因此，考虑到这两个因素，提出了一个新的评分，即年龄/BMI 评分。虽然年龄较大与单变量（OR，1.09 [95%CI 1.05-1.12]，p<0.001）和多变量分析（OR，1.05 [95%CI 1.02-1.09]，p=0.004）中的死亡相关，但与年龄相比，较高的年龄/BMI 评分是死亡的更强预测因素，在单变量（OR 4.42 [95%CI 2.50-7.80]，p<0.001）和多变量分析（OR 3.11 [95%CI 1.66-5.82]，p<0.001）中均如此。有几个因素似乎与 COVID-19 死亡风险有关。有趣的是，我们的新年龄/BMI 评分似乎比年龄 alone 带来更高的死亡风险。这个新的评分将被命名为 Hajeer 评分。由于这是一项小型队列研究，我们建议在更大的队列中研究该评分。
