Nowak-Szczepanska Natalia, Gomula Aleksandra, Sebastjan Anna, Ignasiak Zofia, Malina Robert M, Kozieł Sławomir
Department of Anthropology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Department of Biostructure, Wroclaw University of Health and Sport Sciences, 51-612 Wroclaw, Poland.
Toxics. 2022 Oct 27;10(11):646. doi: 10.3390/toxics10110646.
Environmental pollutions, particularly toxic elements such as lead, are among the most significant factors affecting the growth and functional development of children. The aim of this study was to evaluate the effect of blood lead levels on handgrip strength (HGS) in urban children resident in the Copper Basin of Lower Silesia, Poland, controlling for the effects of chronological age, body size and socioeconomic status. The study included 165 boys (9−11 years of age) and 79 girls (9−10 years of age) from Polkowice town. Anthropometric measurements involved height, body mass and grip strength of the left and right hands. Maternal education was a proxy for socioeconomic status. Based on the median value of blood lead level (3.10 µg/dL), the two groups-below and above/equal median value-were defined. Analysis of covariance revealed that age (all p < 0.001), sex (at least p < 0.01), BMI (all p < 0.001), and blood lead level (at least p < 0.05) had a significant effect on the three indicators of HGS (right hand, left hand, average), while the level of maternal education did not significantly affect HGS (p > 0.05). The results of this study indicate a potentially negative effect of elevated blood lead level on grip strength in preadolescent children, irrespective of sex.
环境污染,尤其是铅等有毒元素,是影响儿童生长和功能发育的最重要因素之一。本研究的目的是评估波兰下西里西亚铜盆地城市儿童血铅水平对手握力(HGS)的影响,同时控制年龄、体型和社会经济地位的影响。该研究纳入了来自波尔科维采镇的165名男孩(9至11岁)和79名女孩(9至10岁)。人体测量包括身高、体重以及左右手的握力。母亲的教育程度作为社会经济地位的代表。根据血铅水平的中位数(3.10微克/分升),定义了两组——低于中位数组和高于/等于中位数组。协方差分析显示,年龄(所有p<0.001)、性别(至少p<0.01)、体重指数(所有p<0.001)和血铅水平(至少p<0.05)对HGS的三个指标(右手、左手、平均值)有显著影响,而母亲的教育程度对HGS没有显著影响(p>0.05)。本研究结果表明,无论性别如何,血铅水平升高对青春期前儿童的握力可能有负面影响。