Park Hee Jun, Geum Sang Yen, Yoo Jae Ho, Park Jin Woo, Shin Seung Heon, Ye Mi Kyung
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu, Daegu, Korea.
Ear Nose Throat J. 2025 Mar;104(1_suppl):275S-278S. doi: 10.1177/01455613221139403. Epub 2022 Nov 10.
Fibrous dysplasia (FD) is a rare benign disease that replaces a normal bone with abnormal fibrous and weak osseous tissue. It is usually detected in childhood and rarely occurs in old age. Although the disease is known to be caused by a genetic mutation, only a single case of FD secondary to surgery is reported in the literature. We report a case of monostotic FD of the maxillary sinus in a 70-year-old Asian woman who presented with incidental calcific lesion in the maxillary sinus on a brain computed tomography scan. At 32 months prior to presentation, the patient had undergone an endoscopic sinus surgery for a fungal ball of the same sinus. The lesion was removed by endoscopic surgery, and the histopathological evidence was consistent with FD. To the best of our knowledge, this is the second case of a postsurgical craniofacial FD, and a rare case that occurred in old age.
骨纤维异常增殖症（FD）是一种罕见的良性疾病，它会用异常的纤维性和脆弱的骨组织替代正常骨骼。该病通常在儿童期被发现，老年时很少发生。尽管已知该疾病由基因突变引起，但文献中仅报道了1例继发于手术的FD病例。我们报告1例70岁亚洲女性上颌窦单骨型FD病例，该患者在脑部计算机断层扫描时偶然发现上颌窦有钙化病变。在就诊前32个月，患者因同一鼻窦的真菌球接受了鼻内镜鼻窦手术。病变通过鼻内镜手术切除，组织病理学证据与FD一致。据我们所知，这是第二例手术后发生的颅面骨纤维异常增殖症，也是罕见的老年发病病例。
