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巨大的咽食管部脂肪肉瘤,有潜在危险。

Hazardous giant pharyngoesophageal liposarcoma.

机构信息

Department of ENT - Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

Department of ENT - Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India

出版信息

BMJ Case Rep. 2022 Nov 10;15(11):e250085. doi: 10.1136/bcr-2022-250085.

Abstract

A man in his early 80s presented to the otorhinolaryngology department with progressively worsening dysphagia to solids and a recent episode of difficulty breathing accompanied by a very brief expulsion of a solid mass from the mouth. Based on the endoscopic appearance of a fatty lesion of an elongated mass with a thick stalk on the posterior pharyngeal wall, a diagnosis of the benign fibrovascular polyp was given after clinical and radiological correlation. The pharyngeal polyp was resected at the base of its pedicle by transoral endoscopy with a thunder beat vessel sealing device. Histopathological examination of the mass revealed a well-differentiated liposarcoma composed of mature adipocytes. Following surgical excision, the patient made a full recovery. This case signifies the integrated role of preoperative biopsy, new surgical technologies and targeted therapies in managing pharyngoesophageal polyps.

摘要

一位 80 岁出头的男性因进行性加重的固体食物吞咽困难和近期呼吸困难发作(伴有一口固体物质的短暂喷出)就诊耳鼻喉科。基于内镜下表现,即后咽壁上有一个带有粗蒂的长形脂肪性病变,在临床和影像学相关性检查后,给出了良性纤维血管息肉的诊断。采用经口内镜下雷射吻合器对咽息肉的蒂部进行切除。肿块的组织病理学检查显示为成熟脂肪细胞组成的分化良好的脂肪肉瘤。在外科切除后,患者完全康复。本例表明术前活检、新型外科技术和靶向治疗在处理咽食管息肉中的综合作用。

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Hazardous giant pharyngoesophageal liposarcoma.巨大的咽食管部脂肪肉瘤,有潜在危险。
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本文引用的文献

1
4
Well-differentiated, pedunculated liposarcoma of the hypopharynx.下咽高分化带蒂脂肪肉瘤
Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Feb;135(1):63-65. doi: 10.1016/j.anorl.2017.07.001. Epub 2017 Jul 29.
7
Liposarcoma: molecular genetics and therapeutics.脂肪肉瘤:分子遗传学与治疗学
Sarcoma. 2011;2011:483154. doi: 10.1155/2011/483154. Epub 2010 Dec 27.
8
Diagnosis and management of lipomatous tumors.脂肪瘤性肿瘤的诊断与管理
J Surg Oncol. 2008 Mar 15;97(4):298-313. doi: 10.1002/jso.20975.
9
Asphyxiation caused by giant fibrovascular polyp of the esophagus.食管巨大纤维血管性息肉导致的窒息
Arch Pathol Lab Med. 2006 May;130(5):725-7. doi: 10.5858/2006-130-725-ACBGFP.

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