Department of Neurosurgery, Renmin Hospital of Wuhan University, No. 238, Jiefang Road, Wuchang District, Wuhan, 430060, Hubei, China.
Department of Critical Care Medicine, Eastern Campus, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Sci Rep. 2022 Nov 10;12(1):19258. doi: 10.1038/s41598-022-22549-7.
To explore the clinical advantages of 3D Slicer combined with Sina/MosoCam multimodal system in preoperative planning of brain lesions surgery. By collecting the data of brain lesions patients undergoing craniotomy under the preoperative positioning of 3D Slicer combined Sina/MosoCam multimodal system in the people's Hospital of Wuhan University from January 2021 to October 2021, the preoperative planning of patients was introduced, and the size of surgical bone window, operation time, preoperative and postoperative neurological dysfunction were counted. We collected the case data of 35 patients who were reconstructed by 3D Slicer and located by Sina/MosoCam projection. There were 14 cases of malignant tumors (7 cases of glioma, 2 cases of diffuse large B-cell lymphoma, 5 cases of metastatic cancer) and 21 cases of benign tumors (17 cases of meningioma, 1 case of central neurocytoma, 2 cases of cavernous hemangioma and 1 case of arachnoid cyst). All 35 patients were located accurately before operation, the lesions were found quickly during operation, and the postoperative imaging data confirmed that the lesions were removed completely, of which 28 cases (80%) had significantly improved neurological symptoms one month after operation. 3D Slicer combined with Sina/MosoCam multimodal system has many advantages, such as simple and easy to learn, convenient operation, accurate positioning and free. It is considered to be a new technology that is practical, reliable, convenient for diagnosis and preoperative planning. It is suitable for popularization and use in neurosurgery and other operating rooms of all medical institutions.
探讨 3D Slicer 联合 Sina/MosoCam 多模态系统在脑病变手术术前规划中的临床优势。通过收集 2021 年 1 月至 2021 年 10 月武汉大学人民医院采用 3D Slicer 联合 Sina/MosoCam 多模态系统行术前定位行开颅手术的脑病变患者资料，介绍患者的术前规划情况，统计手术骨窗大小、手术时间、术前术后神经功能障碍情况。收集 35 例采用 3D Slicer 重建、Sina/MosoCam 投影定位的患者病例资料，其中恶性肿瘤 14 例（胶质瘤 7 例、弥漫性大 B 细胞淋巴瘤 2 例、转移性癌 5 例），良性肿瘤 21 例（脑膜瘤 17 例、中枢神经细胞瘤 1 例、海绵状血管瘤 2 例、蛛网膜囊肿 1 例）。所有患者术前均准确定位，术中迅速找到病灶，术后影像学资料证实病灶完全切除，术后 1 个月 28 例（80%）患者神经功能明显改善。3D Slicer 联合 Sina/MosoCam 多模态系统具有简单易学、操作方便、定位准确、免费等优点，被认为是一种实用、可靠、方便诊断和术前规划的新技术，适用于神经外科及其他医疗机构的手术室推广应用。
