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糖尿病患者下尿路症状评估:一项横断面研究。

An evaluation of lower urinary tract symptoms in diabetic patients: a cross-sectional study.

机构信息

Department of Radiology, An-Najah National University Hospital, Nablus, 44839, Palestine.

Department of Anaesthesia, An-Najah National University Hospital, Nablus, 44839, Palestine.

出版信息

BMC Urol. 2022 Nov 10;22(1):178. doi: 10.1186/s12894-022-01133-1.

Abstract

BACKGROUND

Lower urinary tract symptoms (LUTS) are common among diabetic patients and represent hidden and mysterious morbidity. The pathophysiology of LUTS among diabetes mellitus (DM) patients is multifactorial. Importantly, LUTS is known to cause physical and psychological distress. Thus, this study describes LUTS among DM patients, investigates factors that may associate with it, and assesses the possible relationship between LUTS and the quality of life of diabetics.

METHODS

Over 6 months, data were collected from 378 diabetic patients in primary health care clinics. Demographic and clinical characteristics, Urogenital Distress Inventory-6 (UDI-6), and Incontinence Impact Questionnaire-7 (IIQ-7) were used to collect data. Univariate and multivariate analyses were performed.

RESULTS

Three hundred seventy-eight participants were included in this study. (29.9%) were (58-67) years old. 49% were female. Half of the cohort was overweight, and a third were obese. 81% were Type 2 DM. Almost all of them are on medical treatment. A median score of 5.50 (2.00-8.00) for the UDI-6 scale and a median score of 5 (0.00-10.00) for the IIQ-7 scale were reported. Multiple linear regression models showed that residency (p = 0.038) and regular exercise (p = 0.001) were significantly and negatively correlated with the UDI-6 score, while female gender (p = 0.042), insulin use (p = 0.009) and the presence of comorbidities (p = 0.007) were positively correlated with this score. Furthermore, age (p = 0.040) and body mass index (BMI) (p < 0.001) were significantly and positively associated with the IIQ-7 score.

CONCLUSION

LUTS is significant morbidity among DM patients. Factors such as age, BMI, and co-morbidities exacerbate LUTS, which can be modified and controlled. On the other hand, regular exercise and weight loss strategies help diabetic patients to improve LUTS.

摘要

背景

下尿路症状(LUTS)在糖尿病患者中很常见,代表着隐藏和神秘的发病率。糖尿病患者 LUTS 的病理生理学是多因素的。重要的是,LUTS 已知会引起身体和心理上的痛苦。因此,本研究描述了糖尿病患者的 LUTS,调查了可能与之相关的因素,并评估了 LUTS 与糖尿病患者生活质量之间的可能关系。

方法

在 6 个月的时间里,从初级保健诊所的 378 名糖尿病患者中收集数据。使用尿生殖窘迫量表-6(UDI-6)和尿失禁影响问卷-7(IIQ-7)收集人口统计学和临床特征数据。进行了单变量和多变量分析。

结果

本研究共纳入 378 名参与者。(29.9%)年龄在(58-67)岁之间。49%为女性。一半的患者超重,三分之一的患者肥胖。81%为 2 型糖尿病。他们几乎都在接受药物治疗。UDI-6 量表的中位数评分为 5.50(2.00-8.00),IIQ-7 量表的中位数评分为 5(0.00-10.00)。多线性回归模型显示,居住地(p=0.038)和定期运动(p=0.001)与 UDI-6 评分呈显著负相关,而女性(p=0.042)、使用胰岛素(p=0.009)和存在合并症(p=0.007)与该评分呈正相关。此外,年龄(p=0.040)和体重指数(BMI)(p<0.001)与 IIQ-7 评分呈显著正相关。

结论

LUTS 是糖尿病患者的重要发病率。年龄、BMI 和合并症等因素会加重 LUTS,但可以加以控制。另一方面,定期运动和减肥策略有助于糖尿病患者改善 LUTS。

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