血液透析男性患者的下尿路症状：前瞻性多中心横断面研究
Lower urinary tract symptoms among male patients on hemodialysis: Prospective and multi-central cross-sectional study.
作者信息
Abushamma Faris, Zidan Enas, Douglass Zainab E, Jaber Anas, Nazzal Zaher, Hamdan Zakaria I, Ktaifan Mahfouz, Hashim Hashim
机构信息
Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Urology, An-Najah National University Hospital, Nablus, Palestine.
出版信息
SAGE Open Med. 2024 Jul 30;12:20503121241263302. doi: 10.1177/20503121241263302. eCollection 2024.
BACKGROUND
Lower urinary tract symptoms are common and can significantly impact quality of life, especially in men with co-morbidities and end-stage renal disease. The presence of lower urinary tract symptoms affect the quality of life of patients on hemodialysis.
OBJECTIVES
The purpose of this study is assessing the presence and severity of lower urinary tract symptoms among male patients on hemodialysis. Factors that may exacerbate lower urinary tract symptoms were assessed and studied. The impact of lower urinary tract symptoms on quality of life was also identified.
METHODS
A prospective, multi-central, and cross-sectional study of male patients on hemodialysis was conducted. Demographics, clinical data, and core lower urinary tract symptoms score questionnaire were all collected. A correlation has been made between all variables.
RESULTS
One hundred forty-five patients were enrolled. Eighty-seven percent of hemodialysis patients had at least one storage symptom, and 85% had at least one voiding symptom. The prevalence of storage symptoms (frequency, nocturia, urgency, and urgency incontinence) was found to be 3%, 70%, 44%, and 12%, respectively. The voiding symptoms were mainly weak stream, straining, and incomplete emptying, which were found in 60%, 43%, and 36%, respectively. Fifteen percent of the cohort had a negatively significant impact on their quality of life. The absence of voiding symptoms was statistically linked to a better quality of life ( < 0.05). Hemodialysis patients who are over 60 years old, smokers, or obese were found to be significantly more likely to report storage symptoms (18%, 9%, and 79%, respectively; < 0.05). Bladder pain was significantly correlated to the dialysis duration of more than 24 months ( < 0.05).
CONCLUSION
Storage and voiding lower urinary tract symptoms are common among hemodialysis male patients with a minor impact on their quality of life. Age, smoking, and obesity are major risks of exaggerating such symptoms.
背景
下尿路症状很常见，会显著影响生活质量，尤其是在患有合并症和终末期肾病的男性中。下尿路症状的存在会影响血液透析患者的生活质量。
目的
本研究的目的是评估血液透析男性患者中下尿路症状的存在情况和严重程度。评估并研究了可能加重下尿路症状的因素。还确定了下尿路症状对生活质量的影响。
方法
对血液透析男性患者进行了一项前瞻性、多中心横断面研究。收集了人口统计学、临床数据和核心下尿路症状评分问卷。对所有变量进行了相关性分析。
结果
共纳入145例患者。87%的血液透析患者至少有一种储尿期症状，85%的患者至少有一种排尿期症状。储尿期症状（尿频、夜尿、尿急和急迫性尿失禁）的患病率分别为3%、70%、44%和12%。排尿期症状主要为尿流无力、排尿费力和排空不全，分别占60%、43%和36%。15%的队列对其生活质量有负面影响。无排尿期症状与更好的生活质量在统计学上相关（P<0.05）。发现60岁以上、吸烟或肥胖的血液透析患者报告储尿期症状的可能性显著更高（分别为18%、9%和79%；P<0.05）。膀胱疼痛与透析时间超过24个月显著相关（P<0.05）。
结论
储尿期和排尿期下尿路症状在血液透析男性患者中很常见，对其生活质量影响较小。年龄、吸烟和肥胖是加重此类症状的主要风险因素。
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