Djemai Haidar, Hammad Rami, Dabayebeh Ibrahim M, Hammad Saleh, Merzouk Abdellah, Coumoul Xavier, Noirez Philippe
Institute for Research in bioMedicine and Epidemiology of Sport (IRMES), National Institute of Sport, Expertise, and Performance (INSEP), 11 avenue du Tremblay, Paris, 75012, France.
INSERM UMR-S 1124, Environmental Toxicity, Therapeutic Targets, Cellular Signaling & Biomarkers (T3S), Université Paris Cité, 45 rue des Saints-Pères, Paris, 75006, France.
Arch Public Health. 2022 Nov 10;80(1):231. doi: 10.1186/s13690-022-00983-3.
The emergence and circulation of a novel coronavirus (2019-nCoV)-Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-set off a global health crisis. SARS-CoV-2 spreads faster than its two ancestors, SARS-CoV and MERS-CoV. Several modes of transmission have been identified: via respiratory droplets, contact with infected people or contaminated surfaces, and potentially, bioaerosols. Various countries have taken preventive measures that may include partial or total lockdowns lasting weeks. The physical inactivity associated with lockdowns may promote cardiometabolic or other diseases, while physical activity may play a critical role in preventing them. Here we develop the hypothesis of the involvement of aerosols in the contamination process, the role of angiotensin converting enzyme 2 (ACE2), the potential benefits and harm of physical activity during lockdowns, and we suggest directions for future research.
一种新型冠状病毒（2019 - 新冠病毒）——严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的出现和传播引发了一场全球健康危机。SARS-CoV-2的传播速度比其两个“祖先”——SARS-CoV和MERS-CoV更快。已确定了几种传播方式：通过呼吸道飞沫、与感染者或受污染表面接触，以及可能通过生物气溶胶传播。各国已采取预防措施，其中可能包括持续数周的部分或全面封锁。与封锁相关的身体活动不足可能会促发心血管代谢疾病或其他疾病，而体育活动可能在预防这些疾病方面发挥关键作用。在此，我们提出关于气溶胶在污染过程中的作用、血管紧张素转换酶2（ACE2）的作用、封锁期间体育活动的潜在益处和危害的假说，并为未来研究提出方向。
