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中国儿童患者就诊前非处方抗生素的使用情况:患病率、预测因素以及与就诊时医生开具抗生素处方的关联

Pre-Visit Use of Non-Prescribed Antibiotics among Child Patients in China: Prevalence, Predictors, and Association with Physicians' Prescribing of Antibiotics at Medical Visits.

作者信息

Wang Nan Christine

机构信息

School of Public Administration, Hunan University, Changsha 410082, China.

出版信息

Antibiotics (Basel). 2022 Nov 4;11(11):1553. doi: 10.3390/antibiotics11111553.

DOI:10.3390/antibiotics11111553
PMID:36358207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9687008/
Abstract

Antibiotic resistance is one of the most serious global public health crises. Inappropriate use of antibiotics is an important contributor. Using a cross-sectional survey, we recruited 3056 caregivers from 21 provinces in China to complete a questionnaire pertaining to their most recent medical visits for children's acute respiratory tract infection (ARTI) symptoms in October 2013. The findings show that the prevalence of caregivers giving children non-prescribed antibiotics before their medical visit was as high as 38%. Caring for an older child and having lower educational attainment increased the likelihood of self-medication with antibiotics; among Chinese residential areas, caregivers living in tier 2 urban districts were most likely to administer non-prescribed antibiotics before their visit. Physicians' prescribing of antibiotics was significantly associated with caregivers' self-reported pre-visit use of non-prescribed antibiotics. Misuse should be addressed by regulating the sale of antibiotics and improving communication at medical consultations.

摘要

抗生素耐药性是最严重的全球公共卫生危机之一。抗生素的不当使用是一个重要因素。通过横断面调查,我们从中国21个省份招募了3056名照顾者,让他们填写一份关于2013年10月其孩子因急性呼吸道感染(ARTI)症状最近一次就医情况的问卷。结果显示,照顾者在带孩子就医前给孩子服用非处方抗生素的比例高达38%。照顾年龄较大的孩子以及教育程度较低会增加自行使用抗生素的可能性;在中国各居住地区中,居住在二线城区的照顾者在就医前最有可能给孩子服用非处方抗生素。医生开具抗生素与照顾者自我报告的就医前使用非处方抗生素显著相关。应通过规范抗生素销售和改善医疗咨询中的沟通来解决滥用问题。

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Antibiotics (Basel). 2022 Apr 25;11(5):574. doi: 10.3390/antibiotics11050574.
2
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.2019 年全球细菌对抗菌药物耐药性的负担:系统分析。
Lancet. 2022 Feb 12;399(10325):629-655. doi: 10.1016/S0140-6736(21)02724-0. Epub 2022 Jan 19.
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Going shopping or consulting in medical visits: Caregivers' roles in pediatric antibiotic prescribing in China.去购物还是在就诊时咨询:中国儿科抗生素处方中照顾者的角色。
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Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database study.中国门诊抗生素处方的适宜性:一项全国性描述性数据库研究。
Lancet Infect Dis. 2021 Jun;21(6):847-857. doi: 10.1016/S1473-3099(20)30596-X. Epub 2021 Jan 27.
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