Sigle August, Jilg Cordula A, Weishaar Moritz, Schlenker Boris, Stief Christian, Gratzke Christian, Grabbert Markus
Department of Urology, Faculty of Medicine, Medical Centre, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.
Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, 79085 Freiburg, Germany.
Cancers (Basel). 2022 Oct 26;14(21):5261. doi: 10.3390/cancers14215261.
Introduction: Robot-assisted radical prostatectomy (RARP) is a surgical treatment option for prostate cancer (PC). Quality in RARP depends on the surgeon´s operative volume and expertise. When implementing RARP, it is standard practice to hire a pre-trained surgeon. The aim of our study was to investigate the transferability of quality in RARP. Patients and Methods: We analyzed two consecutive retrospective cohorts of 100 and 108 men, respectively, who underwent RARP at two different centers and on whom surgery was performed by the same surgeon. Results: There were more men with high-grade PC in Cohort 1: 25/100 (25.0%) vs. 9/108 (8.3%), p < 0.01, and infiltration of the seminal vesicles was more frequent (23/100 (23.0%) vs. 10/108 (9.2%), p < 0.01). In Cohort 2, the duration of surgery was shorter and blood loss was lower: 149 (134−174) vs. 172 min (150−196), p < 0.01 and 300 (200−400) vs. 131 (99−188) mL, p < 0.01. No difference was found in the proportion of positive surgical margins in the T2 cohort (8.8% vs. 8.2%, p = 1.00). Conclusion: The procedural and oncological outcome parameters of Cohort 2 do not appear to be inferior to the results obtained for the first cohort. The quality of RARP is transferable if a pre-trained surgeon is hired.
机器人辅助根治性前列腺切除术(RARP)是前列腺癌(PC)的一种手术治疗选择。RARP的质量取决于外科医生的手术量和专业技能。在实施RARP时,聘请经过预培训的外科医生是标准做法。我们研究的目的是调查RARP质量的可转移性。
我们分别分析了两个连续的回顾性队列,各有100名和108名男性,他们在两个不同的中心接受了RARP手术,且手术由同一位外科医生进行。
队列1中高级别PC的男性更多:25/100(25.0%)对比9/108(8.3%),p<0.01,精囊浸润更常见(23/100(23.0%)对比10/108(9.2%),p<0.01)。在队列2中,手术时间更短且失血量更低:149(134 - 174)分钟对比172分钟(150 - 196),p<0.01;300(200 - 400)毫升对比131(99 - 188)毫升,p<0.01。T2队列中手术切缘阳性比例无差异(8.8%对比8.2%,p = 1.00)。
队列2的手术和肿瘤学结局参数似乎并不逊于第一个队列的结果。如果聘请经过预培训的外科医生,RARP的质量是可转移的。