秘鲁南部贫血儿童肠道微生物群的二代测序技术研究
Intestinal Microbiota in Children with Anemia in Southern Peru through Next-Generation Sequencing Technology.
作者信息
Díaz-Rodríguez Karla, Pacheco-Aranibar Jani, Manrique-Sam Cecilia, Ita-Balta Yuma, Carpio-Toia Agueda Muñoz Del, López-Casaperalta Patricia, Chocano-Rosas Teresa, Fernandez-F Fernando, Villanueva-Salas Jose, Bernabe-Ortiz Julio Cesar
机构信息
Post-Graduate School, Universidad Católica de Santa María, Urb. San José s/n, Umacollo, Arequipa 04013, Peru.
Deparment of Biology, Universidad Nacional de San Agustín, Santa Catalina Nro. 117, Arequipa 04001, Peru.
出版信息
Children (Basel). 2022 Oct 25;9(11):1615. doi: 10.3390/children9111615.
Knowledge of the sequencing of the 16S rRNA gene constitutes a true revolution in understanding the composition of the intestinal microbiota and its implication in health states. This study details microbial composition through next-generation sequencing (NGS) technology in children with anemia. Anemia is the most frequent hematological disorder that affects human beings. In Peru, it is one of the conditions that presents the most significant concern due to the adverse effects that cause it, such as delayed growth and psychomotor development, in addition to a deficiency in cognitive development.
16S rRNA基因测序知识在理解肠道微生物群的组成及其对健康状况的影响方面构成了一场真正的革命。本研究通过下一代测序（NGS）技术详细分析了贫血儿童的微生物组成。贫血是影响人类最常见的血液系统疾病。在秘鲁，由于其造成的诸如生长发育迟缓和精神运动发育迟缓以及认知发育缺陷等不良影响，它是最令人担忧的病症之一。
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