Valookaran Aleena Francis, Bouchard Jenny, Aloud Basma Milad, Thandapilly Sijo Joseph, Netticadan Thomas
Morden Research and Development Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada.
Canadian Centre for Agri-Food Research in Health and Medicine, Winnipeg, MB R2H 2A6, Canada.
Molecules. 2022 Oct 25;27(21):7222. doi: 10.3390/molecules27217222.
Hypertension is a common risk factor for cardiovascular disease and mortality worldwide. Proper nutrition and diet are known to play an indispensable role in the treatment and management of hypertension. Bioactive compounds that occur in small quantities in foods such as onions, fish and red wine are being intensively studied to uncover their vasoprotective, antioxidant, anti-proliferative and anti-inflammatory effects which are beneficial to attenuate chronic disease and protect human health. In this article, the anti-hypertensive, and cardio-protective effects of five food-derived bioactive compounds: resveratrol, quercetin, coenzyme Q10, DHA and EPA and their proposed mechanisms of action are reviewed in detail.
高血压是全球心血管疾病和死亡的常见风险因素。众所周知，合理的营养和饮食在高血压的治疗和管理中起着不可或缺的作用。人们正在深入研究洋葱、鱼类和红酒等食物中少量存在的生物活性化合物，以揭示它们的血管保护、抗氧化、抗增殖和抗炎作用，这些作用有助于减轻慢性疾病并保护人类健康。本文详细综述了五种食物来源的生物活性化合物：白藜芦醇、槲皮素、辅酶Q10、二十二碳六烯酸（DHA）和二十碳五烯酸（EPA）的降压和心脏保护作用及其潜在作用机制。
