Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 542/2, 160 00 Prague, Czech Republic.
J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 2155/3, 182 23 Prague, Czech Republic.
Molecules. 2022 Nov 7;27(21):7639. doi: 10.3390/molecules27217639.
The synthesis of a tetrathiafulvalene (TTF) derivative, -[4-({4-[(2,2'-bi-1,3-dithiol-4-ylmethoxy)methyl] phenyl}ethynyl)phenyl] ethanethioate, suitable for the modification of gold nanoparticles (AuNPs), is described in this article. The TTF ligand was self-assembled on the AuNP surface through ligand exchange, starting from dodecanethiol-stabilized AuNPs. The resulting modified AuNPs were characterized by TEM, UV-Vis spectroscopy, and electrochemistry. The most suitable electrochemical method was the phase-sensitive AC voltammetry at very low frequencies of the sine-wave perturbation. The results indicate a diminishing electronic communication between the two equivalent redox centers of TTF and also intermolecular donor-acceptor interactions manifested by an additional oxidation wave upon attachment of the ligand to AuNPs.
本文描述了一种四硫富瓦烯（TTF）衍生物，即 -[4-({4-[(2,2'-联-1,3-二硫醇-4-基)甲氧基]苯基}乙炔基)苯基]乙硫醇酯，适合修饰金纳米粒子（AuNPs）。TTF 配体通过配体交换自组装在 AuNP 表面上，起始于十二硫醇稳定的 AuNPs。所得修饰的 AuNPs 通过 TEM、UV-Vis 光谱和电化学进行表征。最合适的电化学方法是非常低频率的正弦波扰动的相敏交流伏安法。结果表明，TTF 的两个等效氧化还原中心之间的电子通信减弱，并且在配体与 AuNPs 结合时表现出分子间供体-受体相互作用，出现额外的氧化波。
