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预防阿尔茨海默病的饮食:现有知识和未来研究需求。

Diet in the Prevention of Alzheimer's Disease: Current Knowledge and Future Research Requirements.

机构信息

Department of Bromatology, Poznan University of Medical Science, Rokietnicka 3 Street, 60-806 Poznan, Poland.

出版信息

Nutrients. 2022 Oct 30;14(21):4564. doi: 10.3390/nu14214564.

Abstract

Alzheimer's disease is a progressive brain disease that is becoming a major health problem in today's world due to the aging population. Despite it being widely known that diet has a significant impact on the prevention and progression of Alzheimer's disease, the literature data are still scarce and controversial. The application of the principles of rational nutrition for the elderly is suggested for Alzheimer's disease. The diet should be rich in neuroprotective nutrients, i.e., antioxidants, B vitamins, and polyunsaturated fatty acids. Some studies suggest that diets such as the Mediterranean diet, the DASH (Dietary Approaches to Stop Hypertension) diet, and the MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet have a beneficial effect on the risk of developing Alzheimer's disease.

摘要

阿尔茨海默病是一种进行性脑疾病,由于人口老龄化,它正在成为当今世界的一个主要健康问题。尽管人们普遍认为饮食对预防和进展阿尔茨海默病有重大影响,但文献数据仍然很少且存在争议。建议将老年人合理营养原则应用于阿尔茨海默病。饮食应富含神经保护营养素,即抗氧化剂、B 族维生素和多不饱和脂肪酸。一些研究表明,地中海饮食、DASH(停止高血压的饮食方法)饮食和 MIND(地中海-DASH 干预以延缓神经退行性疾病)饮食等饮食对降低阿尔茨海默病的发病风险有有益影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/001a/9656789/2636b4e5f445/nutrients-14-04564-g001.jpg

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