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在 COVID-19 大流行的激增 2 期间,在一家三级转诊教学医院开展、实施和评估为期七天的临床药学服务。

Development, implementation and evaluation of a seven-day clinical pharmacy service in a tertiary referral teaching hospital during surge-2 of the COVID-19 pandemic.

机构信息

Pharmacy Department, Kings College Hospital, London, SE5 9RS, UK.

Institute of Pharmaceutical Sciences and Institute of Psychiatry, Psychology, Neurosciences Kings College London, London, SE1 9RT, UK.

出版信息

Int J Clin Pharm. 2023 Apr;45(2):293-303. doi: 10.1007/s11096-022-01475-8. Epub 2022 Nov 11.

Abstract

BACKGROUND

Seven-day clinical pharmacy services in the acute sector of the National Health Service are limited. There is a paucity of evidential patient benefit. This limits investment and infrastructure, despite United Kingdom wide calls.

AIM

To optimise medicines seven-days a week during surge-2 of the COVID-19 pandemic through implementation of a seven-day clinical pharmacy service. This paper describes service development, evaluation and sustainability.

SETTING

A tertiary-referral teaching hospital, London, United Kingdom.

DEVELOPMENT

The seven-day clinical pharmacy service was developed to critical care, acute and general medical patients. Clinical leads developed the service specification and defined priorities, targeting complex patients and transfer of care. Contributing staff were briefed and training materials developed.

IMPLEMENTATION

The service was implemented in January 2021 for 11 weeks. Multidisciplinary team communication brought challenges; strategies were employed to overcome these.

EVALUATION

A prospective observational study was conducted in intervention wards over two weekends in February 2021. 1584 beds were occupied and 602 patients included. 346 interventions were reported and rated; 85.6% had high or moderate impact; 56.7% were time-critical. The proportion of medicines reconciliation within 24-h of admission was analysed across the hospital between November 2020 and May 2021. During implementation, patients admitted Friday-Sunday were more likely to receive medicines reconciliation within 24-h (RR 1.41 (95% CI 1.34-1.47), p < 0.001). Rostered services were delivered sustainably in terms of shift-fill rate and medicines reconciliation outcome.

CONCLUSION

Seven-day clinical pharmacy services benefit patient outcome through early medicines reconciliation and intervention. Investment to permanently embed the service was sustained.

摘要

背景

英国国民保健制度急性部门的七天临床药学服务有限。缺乏有证据表明对患者有益的服务。尽管英国各地都有呼声,但这限制了投资和基础设施建设。

目的

通过实施七天临床药学服务,在 COVID-19 大流行的激增 2 期内每周 7 天优化药物治疗。本文介绍了服务的开发、评估和可持续性。

地点

英国伦敦的一所三级转诊教学医院。

发展

七天临床药学服务是为重症监护、急性和普通内科患者开发的。临床负责人制定了服务规范并确定了优先事项,重点是复杂患者和护理交接。为相关工作人员提供了简报和培训材料。

实施

该服务于 2021 年 1 月在 11 个星期内实施。多学科团队之间的沟通带来了挑战;采取了策略来克服这些挑战。

评估

在 2021 年 2 月的两个周末,在干预病房进行了一项前瞻性观察研究。共有 1584 张床位,收治了 602 名患者。报告和评估了 346 项干预措施;85.6%具有较高或中度影响;56.7%为时间关键型。分析了 2020 年 11 月至 2021 年 5 月期间医院内所有入院患者的药物重整在 24 小时内完成的比例。在实施期间,周五至周日入院的患者更有可能在 24 小时内完成药物重整(RR 1.41(95%CI 1.34-1.47),p<0.001)。轮班服务在轮班填补率和药物重整结果方面得以可持续提供。

结论

七天临床药学服务通过早期药物重整和干预使患者受益。投资永久嵌入该服务得以持续。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/667c/10147787/d69a3cda7cda/11096_2022_1475_Fig1_HTML.jpg

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