一种用于形成amphisome 的植物特异性桥接衔接蛋白。

A plant-specific bridging adaptor for amphisome biogenesis.

机构信息

Louvain Institute of Biomolecular Science and Technology (LIBST), University of Louvain, Louvain-la-Neuve, Belgium.

出版信息

J Cell Biol. 2022 Dec 5;221(12). doi: 10.1083/jcb.202210011. Epub 2022 Nov 11.

DOI:10.1083/jcb.202210011

PMID:36367702

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9663972/

Abstract

The fusion of autophagosomes with endocytic compartments to form amphisomes has only been described in metazoans. In this issue, Zhao et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202203139) demonstrate the existence of amphisomes in the plant cell and identify a plant-specific adaptor protein, CFS1, that mediates their biogenesis.

摘要

自噬体与内吞体融合形成内涵体仅在后生动物中被描述过。在本期杂志中，Zhao 等人（2022. J. Cell Biol.https://doi.org/10.1083/jcb.202203139）证明了内涵体在植物细胞中的存在，并鉴定出一种植物特异性衔接蛋白 CFS1，该蛋白介导了它们的生物发生。