Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA.
CDC Foundation, Atlanta, GA; Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA.
Am J Obstet Gynecol. 2023 Mar;228(3):315.e1-315.e14. doi: 10.1016/j.ajog.2022.10.046. Epub 2022 Nov 9.
Insurance coverage for fertility services may reduce the financial burden of high-cost fertility care such as assisted reproductive technology and improve its utilization. Patients who exit care after failing to reach their reproductive goals report higher rates of mental health problems and a lower sense of well-being. It is important to understand the relationship between state-mandated insurance coverage for fertility services and assisted reproductive technology care discontinuation.
This study aimed to assess whether state-mandated insurance coverage for fertility services is associated with lower rates of care discontinuation after an initial assisted reproductive technology cycle that did not result in a live birth.
This is a retrospective, population-based cohort study using data from United States fertility clinics reporting to the National Assisted Reproductive Technology Surveillance System during 2016 and 2018. Patients who began their first autologous assisted reproductive technology cycle during 2016 and 2017 and did not have a live birth were included. We describe the rate of assisted reproductive technology care discontinuation (no additional cycle within 12 months of the previous cycle's date of failure). Multivariable analyses were conducted to evaluate factors independently associated with care discontinuation, including the scope of fertility services included in state coverage mandate at assisted reproductive technology cycle initiation that were as follows: comprehensive (≥3 assisted reproductive technology cycles), limited (1, 2, or an unspecified number of assisted reproductive technology cycles), mandate not including assisted reproductive technology, and no mandate.
Among 91,324 patients who underwent their first autologous assisted reproductive technology cycle that did not result in live birth, 24,072 (26.4%) discontinued care. Compared with patients who lived in states with mandates for comprehensive assisted reproductive technology coverage, those in states with mandates for fertility services coverage that did not include assisted reproductive technology or states with no mandate were 46% (adjusted relative risk, 1.46; 95% confidence interval, 1.31-1.63) and 26% (adjusted relative risk, 1.26; 95% confidence interval, 1.15-1.39) more likely to discontinue care, respectively, after controlling for patient and cycle characteristics. Increasing patient age, distance from clinic ≥50 miles, previous live birth, fewer oocytes retrieved, and not having embryos cryopreserved were also associated with higher rates of discontinuation. Non-Hispanic Black, non-Hispanic Asian, and Hispanic patients had higher rates of care discontinuation than non-Hispanic White patients regardless of the existence or scope of state-mandated assisted reproductive technology coverage.
Comprehensive state-mandated insurance coverage for assisted reproductive technology is associated with lower rates of assisted reproductive technology care discontinuation.
生育服务保险的覆盖范围可能会减轻高成本生育护理(如辅助生殖技术)的经济负担,并提高其利用率。未能实现生殖目标后退出护理的患者报告心理健康问题发生率更高,幸福感更低。了解州政府强制要求的生育服务保险覆盖范围与辅助生殖技术护理中断之间的关系非常重要。
本研究旨在评估州政府强制要求的生育服务保险覆盖范围是否与首次未导致活产的辅助生殖技术周期后护理中断率降低有关。
这是一项使用美国生育诊所向国家辅助生殖技术监测系统报告的数据进行的回顾性、基于人群的队列研究,数据来源于 2016 年和 2018 年。纳入的患者在 2016 年和 2017 年开始他们的第一次自体辅助生殖技术周期,且未活产。我们描述了辅助生殖技术护理中断率(在之前周期失败日期的 12 个月内没有进行其他周期)。进行多变量分析以评估与护理中断独立相关的因素,包括在辅助生殖技术周期开始时纳入州覆盖范围授权的生育服务范围,包括:全面(≥3 个辅助生殖技术周期)、有限(1、2 或未指定数量的辅助生殖技术周期)、未授权包括辅助生殖技术以及没有授权。
在 91324 名接受首次未导致活产的自体辅助生殖技术周期的患者中,有 24072 名(26.4%)中断了护理。与生活在全面辅助生殖技术覆盖范围授权的州的患者相比,生活在未授权或没有授权的州的患者分别有 46%(调整后的相对风险,1.46;95%置信区间,1.31-1.63)和 26%(调整后的相对风险,1.26;95%置信区间,1.15-1.39)更有可能在控制患者和周期特征后中断护理。患者年龄增加、距离诊所≥50 英里、既往活产、获卵数较少以及未冷冻胚胎也与更高的中断率相关。非西班牙裔黑人、非西班牙裔亚裔和西班牙裔患者无论州政府是否强制要求辅助生殖技术覆盖范围以及覆盖范围如何,其护理中断率均高于非西班牙裔白人患者。
全面的州政府强制要求的辅助生殖技术保险覆盖范围与辅助生殖技术护理中断率降低有关。