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沙鼠生殖功能研究进展:综述。

Progress in research on the reproductive function in the sand rat (Psammomys obesus): A review.

机构信息

USTHB. University of Sciences and Technology of Houari Boumediene, Biological Sciences Faculty, Arid Area Research Laboratory, Algiers, Algeria.

Department of Applied Biology, College of Sciences, University of Sharjah, Sharjah, United Arab Emirates; Human Genetics & Stem Cells Research Group, Research Institute of Sciences & Engineering, University of Sharjah, Sharjah, United Arab Emirates; Molecular Genetics Research Laboratory, University of Sharjah, Sharjah, United Arab Emirates.

出版信息

Gen Comp Endocrinol. 2023 Jan 15;331:114161. doi: 10.1016/j.ygcen.2022.114161. Epub 2022 Nov 9.

DOI:10.1016/j.ygcen.2022.114161
PMID:36368440
Abstract

The Fat Sand Rat (Psammomys obesus, P. obesus) is a diurnal herbivore and phytophage, with seasonal reproductive behavior. The sexually active phase lasts from autumn to early spring and the sexually inactive phase from late spring to summer. In the past years, P. obesus has gained much attention as an animal model in biological and clinical research. It is a suitable model for diet-induced insulin resistance, non-insulin-dependent diabetes mellitus and obesity studies. In addition, the seasonal reproduction of P. obesus is gaining more and more attention. The current paper aims to review and sum up the progress in the understanding of the reproductive anatomo-histo-physiology of Psammomys obesus, in order to facilitate future research in this area and to expose further perspectives for researchers.

摘要

沙鼠(Psammomys obesus,P. obesus)是一种昼行性草食性植食性动物,具有季节性繁殖行为。性活跃期从秋季持续到早春,而性不活跃期从春末持续到夏季。在过去的几年中,沙鼠作为生物和临床研究中的动物模型引起了广泛关注。它是用于研究饮食诱导的胰岛素抵抗、非胰岛素依赖型糖尿病和肥胖症的理想模型。此外,沙鼠的季节性繁殖也越来越受到关注。本文旨在综述和总结沙鼠生殖解剖组织生理学方面的研究进展,以促进该领域未来的研究,并为研究人员提供进一步的研究视角。

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1
Progress in research on the reproductive function in the sand rat (Psammomys obesus): A review.沙鼠生殖功能研究进展:综述。
Gen Comp Endocrinol. 2023 Jan 15;331:114161. doi: 10.1016/j.ygcen.2022.114161. Epub 2022 Nov 9.
2
Ob (obese) gene expression and leptin levels in Psammomys obesus.肥胖沙鼠中Ob(肥胖)基因表达和瘦素水平。
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Diet-induced diabetes in the sand rat (Psammomys obesus).饮食诱导沙鼠(肥尾沙鼠)患糖尿病。
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Psammomys obesus and the albino rat--two different models of nutritional insulin resistance, representing two different types of human populations.欧黄鼠和白化大鼠——营养性胰岛素抵抗的两种不同模型,代表两种不同类型的人群。
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Diet-induced insulin resistance state disturbs brain clock processes and alters tuning of clock outputs in the Sand rat, Psammomys obesus.饮食诱导的胰岛素抵抗状态扰乱了沙鼠大脑时钟进程,并改变了沙鼠时钟输出的调谐。
Brain Res. 2018 Jan 15;1679:116-124. doi: 10.1016/j.brainres.2017.11.018. Epub 2017 Dec 22.

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