Department of Neurology, The Third Hospital of Shijiazhuang, 050000, Shijiazhuang, Hebei, China.
Department of Emergency, Hengshui People's Hospital, 053000, Hengshui, Hebei, China.
BMC Neurol. 2022 Nov 11;22(1):421. doi: 10.1186/s12883-022-02959-w.
Meningoencephalocele is a rare malformation caused by congenital and acquired lesions. The association between recurrent bacterial meningitis and meningoencephaloceles with cerebrospinal fluid (CSF) leak is reported in the literature. We report a rare case of meningoencephalocele secondary to chronic idiopathic intracranial hypertension as a result of hospitalization repeatedly for meningitis due to the lack of CSF leak.
This study presents a case of a patient with a decade of recurrent meningitis. With clinical symptoms and imaging examination with chronic idiopathic intracranial hypertension, this patient was diagnosed with meningoencephalocele. With the treatment of acetazolamide to decrease CSF product, the patient had no recurrence of meningitis over the 6-months follow-up period.
In patients with recurrent intracranial infections but no history of immunodeficiency, cranial trauma, or neurosurgery, the possibility of meningitis should be considered appropriately, even in the absence of CSF otorrhea or rhinorrhea.
脑脊膜脑膨出是一种罕见的先天和后天性病变引起的畸形。文献中有复发性细菌性脑膜炎与伴有脑脊液（CSF）漏的脑脊膜脑膨出相关联的报道。我们报告了一例罕见的因反复发生脑膜炎而住院导致慢性特发性颅内高压继发脑脊膜脑膨出的病例，其原因是缺乏 CSF 漏。
本研究报告了一例患有十年复发性脑膜炎的患者。该患者有慢性特发性颅内高压的临床症状和影像学检查，诊断为脑脊膜脑膨出。用乙酰唑胺降低 CSF 产量治疗后，该患者在 6 个月的随访期间没有再次发生脑膜炎。
在没有免疫缺陷、颅脑创伤或神经外科手术史的复发性颅内感染患者中，即使没有 CSF 耳漏或鼻漏，也应适当考虑脑膜炎的可能性。
