Wang Zheyu, Yao Yao, Wang Fen
Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, PR China.
Department of Gastroenterology, Zhangjiajie People's Hospital, Zhangjiajie 427000, PR China.
Int J Surg Case Rep. 2022 Nov;100:107774. doi: 10.1016/j.ijscr.2022.107774. Epub 2022 Nov 7.
Crohn's disease (CD) is a chronic gastrointestinal granulomatous disease. When CD is complicated by abscess formation, the most quality of life of patients were seriously affected, especially those with intestinal fistula, intestinal stenosis or severe disease activity.
We present a case of a 20-year-old male with CD associated with intestinal fistula and psoas muscle abscess formation, who was successfully managed by drugs and nutrition without surgery.
Surgery is undoubtedly the most effective treatment for CD with abscesses/fistulas. Whereas, for patients sensitive to drug therapy, abscess puncture and drainage could be considered as alternative to surgery, at this time enteral nutrition, antibiotics and immunosuppressants is particularly critical.
We suggest that CD patients complicated with abscess formation in clinical, if the infection can be controlled before operation, and the abscess site is convenient for puncture and drainage, who could consider to choose comprehensive treatment like enteral nutrition, antibiotics, continuous local irrigation of the abscess cavity via the catheter and immunosuppressive agents.
克罗恩病(CD)是一种慢性胃肠道肉芽肿性疾病。当CD并发脓肿形成时,患者的生活质量大多受到严重影响,尤其是那些伴有肠瘘、肠道狭窄或疾病活动严重的患者。
我们报告一例20岁男性CD患者,伴有肠瘘和腰大肌脓肿形成,通过药物和营养治疗成功治愈,未进行手术。
手术无疑是治疗CD合并脓肿/瘘管最有效的方法。然而,对于对药物治疗敏感的患者,脓肿穿刺引流可被视为手术的替代方法,此时肠内营养、抗生素和免疫抑制剂尤为关键。
我们建议临床中CD合并脓肿形成的患者,如果术前能控制感染,且脓肿部位便于穿刺引流,可考虑选择肠内营养、抗生素、经导管持续局部冲洗脓肿腔及免疫抑制剂等综合治疗。