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叶黄素与碳点结合可显著提高光稳定性和抗氧化保护作用。

The remarkable enhancement of photo-stability and antioxidant protection of lutein coupled with carbon-dot.

机构信息

Chemistry and Material Engineering College, Beijing Technology and Business University, Beijing 100048, China.

出版信息

Food Chem. 2023 Mar 30;405(Pt A):134551. doi: 10.1016/j.foodchem.2022.134551. Epub 2022 Oct 8.


DOI:10.1016/j.foodchem.2022.134551
PMID:36371390
Abstract

Lutein is a carotenoid that is beneficial to human health. However, its low stability and bioavailability have limited its application in the pharmaceutical and food industries. Herein, lutein has been successfully modified with carbon-dots (CDs) via a simple and mild solvent-ultrasonic method at room temperature. The synthesized lutein/CDs composites (LCs) showed 3.4 times higher photostability than the pristine lutein under UV irradiation, and 3.5 times higher than that under visible light, and the retention rate of lutein in the air rose from 3.6 % to 68 % over 25 days. Meanwhile, the antioxidant capacity of lutein has been improved by 6.4 times. Based on the photoluminescence (PL) measurements, a possible mechanism for the enhanced photostability and antioxidant ability of LCs has been proposed. The work provides a simple but effective approach to enhancing the stability and antioxidant capacity of lutein, and is expected to extend its application in food and biomedical fields.

摘要

叶黄素是一种对人体健康有益的类胡萝卜素。然而,其低稳定性和生物利用度限制了其在制药和食品工业中的应用。在此,通过简单温和的室温溶剂超声法,成功地将叶黄素用碳点(CDs)进行了修饰。合成的叶黄素/碳点复合材料(LCs)在紫外线照射下的光稳定性比原叶黄素提高了 3.4 倍,在可见光下提高了 3.5 倍,叶黄素在空气中的保留率从 25 天内的 3.6%提高到 68%。同时,叶黄素的抗氧化能力提高了 6.4 倍。基于光致发光(PL)测量,提出了 LCs 增强光稳定性和抗氧化能力的可能机制。该工作为提高叶黄素的稳定性和抗氧化能力提供了一种简单而有效的方法,有望扩展其在食品和生物医学领域的应用。

相似文献

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The remarkable enhancement of photo-stability and antioxidant protection of lutein coupled with carbon-dot.

Food Chem. 2023-3-30

[2]
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[3]
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[4]
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[6]
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[7]
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[8]
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[9]
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[10]
Pharmacokinetic properties of lutein emulsion after oral administration to rats and effect of food intake on plasma concentration of lutein.

Biopharm Drug Dispos. 2011-2-15

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J Fluoresc. 2025-6-20

[2]
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[3]
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[4]
Lutein Loaded in β-Cyclodextrin Metal-Organic Frameworks for Stability and Solubility Enhancements.

AAPS PharmSciTech. 2024-6-11

[5]
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Curr Res Food Sci. 2024-5-3

[6]
Natural biomass-derived carbon dots as a potent solubilizer with high biocompatibility and enhanced antioxidant activity.

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[7]
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