Özgür D S, Akkuzu G, Yildirim F, Yalçin Mutlu M, Karaali Oğlu B, Erdoğan M, Bes C
University of Health Sciences, Başakşehir Çam and Sakura City Hospital, Department of Rheumatology, Istanbul, Turkey.
Clin Ter. 2022 Nov-Dec;173(6):500-502. doi: 10.7417/CT.2022.2469.
Relapsing polychondritis (RP) is a a rare multisystemic disease and it affects cartilaginous tissue and proteoglycan rich organs. The spectrum of clinical features are intermittent inflammation involving especially the auricular and nasal regions. In some patients with RP, systemic vasculitis, autoimmune diseases or malignancy may accompany. Although rare, any of the ANCA-associated vasculitis have been reported in patients with RP. Eosinophilic granulomatous with polyangiitis (EGPA) is a multisystem small vessel vasculitis associated with asthma and eosinophilia. Here we present a case of coexistence of RP and EGPA.
复发性多软骨炎(RP)是一种罕见的多系统疾病,它会影响软骨组织和富含蛋白聚糖的器官。临床特征谱为间歇性炎症,尤其累及耳部和鼻部区域。在一些RP患者中,可能伴有系统性血管炎、自身免疫性疾病或恶性肿瘤。虽然罕见,但RP患者中已报告有任何一种抗中性粒细胞胞浆抗体(ANCA)相关血管炎。嗜酸性肉芽肿性多血管炎(EGPA)是一种与哮喘和嗜酸性粒细胞增多相关的多系统小血管血管炎。在此,我们报告一例RP与EGPA共存的病例。