脑肠行为治疗的未来：中介和调节因素。
Future of Brain-Gut Behavior Therapies: Mediators and Moderators.
机构信息
Division of Gastroenterology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Nobels väg 9, Solna, Stockholm 171 65, Sweden.
出版信息
Gastroenterol Clin North Am. 2022 Dec;51(4):723-739. doi: 10.1016/j.gtc.2022.06.011. Epub 2022 Oct 20.
With growing evidence to support their efficacy, brain-gut behavior therapies are increasingly viewed as a key component to integrated care management of disorders of gut-brain interaction. However, the types of brain-gut behavior therapies differ in how and for whom they purportedly work. We provide a conceptual review of these brain-gut behavior therapies, with an emphasis on describing how (ie, mechanisms) and for whom (ie, moderators) they work as hypothesized and/or supported by evidence. Based on evidence to date, we recommend that brain-gut behavior therapies prioritize gastrointestinal-specific targets, such as gastrointestinal-specific anxiety.
随着越来越多的证据支持其疗效，脑肠行为疗法越来越被视为综合管理肠脑相互作用障碍的关键组成部分。然而，脑肠行为疗法的类型在其据称的作用方式和适用人群上有所不同。我们对这些脑肠行为疗法进行了概念性综述，重点描述了它们的作用机制（即机制）和适用人群（即调节剂），这些作用方式是基于假设和/或现有证据支持的。基于目前的证据，我们建议脑肠行为疗法优先考虑胃肠道特异性靶点，如胃肠道特异性焦虑。
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