Kennon S, Tasch E G, Arm R N
J Am Dent Assoc. 1978 Oct;97(4):641-3. doi: 10.14219/jada.archive.1978.0332.
Among the undesirable effects associated with the use of oral contraceptives are an increased incidence of thromboembolic events, an increased risk of myocardial infarction, and, in certain users, a significant elevation in blood pressure. An altered fibrinolytic activity may have a direct effect on the occurrence of localized osteitis, "dry sockets." It is also possible that gingival inflammation and loss of attachment may occur even under conditions of adequate plaque control. Salivary changes and alterations in the bony trabecular pattern of the mandible have been observed, but the clinical significance is as yet undetermined (Illustration).
与口服避孕药使用相关的不良影响包括血栓栓塞事件发生率增加、心肌梗死风险增加，以及某些使用者血压显著升高。纤溶活性改变可能对局限性骨炎即“干槽症”的发生有直接影响。即使在菌斑控制良好的情况下，也有可能发生牙龈炎症和附着丧失。已观察到唾液变化和下颌骨骨小梁模式改变，但其临床意义尚未确定（图）。
