对于移植前微小残留病的中危和高危急性髓系白血病患者，单倍体同基因移植相较于人类白细胞抗原匹配的同胞供体移植具有更低的复发率和更好的生存优势。 - Suppr | 超能文献

相似文献

1

The lower relapse rate and better survival advantages of haploidentical allograft compared with HLA-matched sibling donor allografts for intermediate- and adverse-risk AML patients with pretransplantation minimal residual disease.对于移植前微小残留病的中危和高危急性髓系白血病患者，单倍体同基因移植相较于人类白细胞抗原匹配的同胞供体移植具有更低的复发率和更好的生存优势。

Bone Marrow Transplant. 2023 Feb;58(2):215-218. doi: 10.1038/s41409-022-01872-7. Epub 2022 Nov 14.

2

Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis.采用多参数流式细胞术检测，单倍体同种异体移植优于匹配的同胞供体移植，可根除 AML 患者移植前微小残留病：回顾性和前瞻性分析。

J Hematol Oncol. 2017 Jul 4;10(1):134. doi: 10.1186/s13045-017-0502-3.

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Outcomes of hematopoietic stem cell transplantation from unmanipulated haploidentical versus matched sibling donor in patients with acute myeloid leukemia in first complete remission with intermediate or high-risk cytogenetics: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.未经调控的单倍体相合与同胞相合供者造血干细胞移植治疗伴有中高危细胞遗传学异常的急性髓系白血病患者在首次完全缓解后的结果：来自欧洲血液和骨髓移植学会急性白血病工作组的一项研究。

Haematologica. 2018 Aug;103(8):1317-1328. doi: 10.3324/haematol.2018.189258. Epub 2018 May 10.

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Comparison of the safety and efficacy of prophylactic donor lymphocyte infusion after haploidentical versus matched-sibling PBSCT in very high-risk acute myeloid leukemia.在极高危急性髓系白血病患者中，比较亲缘单倍体与同胞相合供者 PBSCT 后预防性供者淋巴细胞输注的安全性和有效性。

Ann Hematol. 2019 May;98(5):1267-1277. doi: 10.1007/s00277-019-03636-8. Epub 2019 Feb 12.

5

Haploidentical transplantation might have superior graft-versus-leukemia effect than HLA-matched sibling transplantation for high-risk acute myeloid leukemia in first complete remission: a prospective multicentre cohort study.HLA 单倍型相合移植可能比 HLA 匹配同胞移植在高危急性髓系白血病首次完全缓解后具有更好的移植物抗白血病效应：一项前瞻性多中心队列研究。

Leukemia. 2020 May;34(5):1433-1443. doi: 10.1038/s41375-019-0686-3. Epub 2019 Dec 12.

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Stem cell transplantation from a haploidentical donor versus a genoidentical sister for adult male patients with acute myelogenous leukemia in first remission: A retrospective study from the acute leukemia working party of the European Society for Blood and Marrow Transplantation.来自半相合供体与基因相合同胞供体的造血干细胞移植治疗成人男性急性髓系白血病患者首次完全缓解：来自欧洲血液和骨髓移植学会急性白血病工作组的一项回顾性研究。

Cancer. 2020 Mar 1;126(5):1004-1015. doi: 10.1002/cncr.32629. Epub 2019 Nov 27.

7

Unmanipulated haploidentical versus HLA-matched sibling allogeneic hematopoietic stem cell transplantation in relapsed/refractory acute myeloid leukemia: a retrospective study on behalf of the ALWP of the EBMT.未处理的单倍体相合与 HLA 匹配的同胞异基因造血干细胞移植治疗复发/难治性急性髓系白血病：一项代表 EBMT 的 ALWP 的回顾性研究。

Bone Marrow Transplant. 2019 Sep;54(9):1499-1510. doi: 10.1038/s41409-019-0459-7. Epub 2019 Feb 4.

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Haploidentical unrelated allogeneic stem cell transplantation for relapsed/refractory acute myeloid leukemia: a report on 1578 patients from the Acute Leukemia Working Party of the EBMT.亲缘半相合非亲缘异基因造血干细胞移植治疗复发/难治性急性髓系白血病：来自 EBMT 急性白血病工作组的 1578 例患者报告。

Haematologica. 2019 Mar;104(3):524-532. doi: 10.3324/haematol.2017.187450. Epub 2018 Oct 25.

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Comparison of Autologous Stem Cell Transplantation versus Haploidentical Donor Stem Cell Transplantation for Favorable- and Intermediate-Risk Acute Myeloid Leukemia Patients in First Complete Remission.在首次完全缓解的中低危急性髓系白血病患者中，比较自体造血干细胞移植与单倍体相合供者造血干细胞移植。

Biol Blood Marrow Transplant. 2018 Apr;24(4):779-788. doi: 10.1016/j.bbmt.2017.12.796. Epub 2017 Dec 28.

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Allogeneic hematopoietic stem cell transplantation for intermediate-risk acute myeloid leukemia in the first remission: outcomes using haploidentical donors are similar to those using matched siblings.同种异体造血干细胞移植治疗首次缓解期中危急性髓系白血病：与同胞供者相比，使用单倍体相合供者的结果相似。

Ann Hematol. 2021 Feb;100(2):555-562. doi: 10.1007/s00277-020-04359-x. Epub 2021 Jan 7.

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Abnormal metabolic activation of CD8 T cells correlates with poor prognosis in acute myeloid leukemia.CD8 T细胞的异常代谢激活与急性髓系白血病的不良预后相关。

J Transl Med. 2025 Jul 14;23(1):791. doi: 10.1186/s12967-025-06833-4.

2

Lack of Evidence Supporting a Significant Benefit of Pre-Transplant Consolidation Therapy in AML CR2 Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.缺乏证据支持移植前巩固治疗对接受异基因造血干细胞移植的急性髓系白血病完全缓解2期患者有显著益处。

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3

Fifty years of BMT: risk stratification, donor matching, and stem cell collection for transplantation.