Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, University of Toyama, Toyama, Japan.
Department of Oral and Maxillofacial Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Cleft Palate Craniofac J. 2024 Jan;61(1):155-158. doi: 10.1177/10556656221138886. Epub 2022 Nov 14.
Ankyloblepharon filiforme adnatum (AFA) is a rare, benign congenital anomaly. Notably, it is characterized by the adhesion of the ciliary edges of the upper and lower eyelids at the trabecular line. AFA is usually a solitary malformation of sporadic occurrence; however, it can occur in conjunction with other congenital diseases. Herein, we report a case of cleft lip with AFA. A patient was referred to the ophthalmology department of our hospital. The ophthalmic diagnosis was AFA in both the eyes. The left eye was observed to have a fibrous adhesion in the center, and she underwent surgery to excise the fibrous adhesion of tissue with scissors. The right eye was observed to have a fibrous adhesion in the external canthus and was excised during lip plasty. After surgery, her eyes were able to fully open, and no other apparent disease was diagnosed. AFA is thought to be caused by an ectodermal-derived developmental abnormality. Notably, cases of AFA with a cleft lip are rare. Diagnosis and surgery should be performed promptly to minimize any risk of amblyopia and for the early detection of congenital diseases, including glaucoma.
先天性动眼脸动不能（AFA）是一种罕见的良性先天异常。值得注意的是，其特征是在小梁线上上、下眼睑的睫毛边缘粘连。AFA 通常是一种孤立的、散发性畸形；然而，它也可能与其他先天性疾病同时发生。在此，我们报告一例 AFA 合并唇裂的病例。一名患者被转至我院眼科就诊。眼科诊断为双眼 AFA。左眼中央可见纤维性粘连，行手术用剪刀切除纤维性粘连组织。右眼外眦可见纤维性粘连，在唇裂修复术中切除。术后，患者双眼能完全睁开，未诊断出其他明显疾病。AFA 被认为是由外胚层来源的发育异常引起的。值得注意的是，AFA 合并唇裂的病例较为罕见。应及时进行诊断和手术，以最大限度地降低弱视风险，并早期发现包括青光眼在内的先天性疾病。
