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[国立医疗中心血库免疫血液学的外部质量控制。历史与现状]

[External Quality Control in Immunohematology of National Medical Center's Blood Bank. History and present].

作者信息

Castillo-Mercado Isabel, Galván-Bobadilla Alexis Ignacio, Bonilla-Zavala Ruth, González-Moreno Elizabeth, Sánchez-Cañas José Alberto, Villegas-Martínez Rita, Castillo-Albarrán Fátima Martha, Benítez-Arvizu Gamaliel

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2023 Jan 1;61(Suppl 1):S59-S64.

Abstract

For the proper functioning of the Immunohematology Area, an External Quality Control was established since 1973 through a program that evaluates the performance of the laboratories of the Blood Bank and transfusion services that carry out immunohematology tests. This program consists of sending panel cells to participating blood banks or services, which are phenotyped erythrocyte samples previously studied as problem cases but whose results are unknown by the participating laboratories. The processes in which the program is of most importance are determination of the ABO group, determination of Rh, performance of the direct and indirect Coombs test, and pre-transfusion compatibility tests. It was carried out an observational and retrospective study of the results obtained in the 2020 period from 104 units participating in the Immunohematology Quality Control Program of the National Medical Center's Blood Bank. A panel of cells was sent for external quality control of immunohematology every 45 days, resulting in 9 panels for each unit in the studied period. Compliance with the program was observed in the general result (79.6%), i.e., there was a decrease in the participation of the registered units. Of a maximum score of 100% to be obtained, it was observed a general result of 95.3% compliance of the participating units. The results obtained confirm the good general training of the immunohematology laboratories of the participating units. Yet, as in any external control program, it becomes clear that obtaining an erroneous result is a risk that can occur in any laboratory.

摘要

为确保免疫血液学领域的正常运作,自1973年起通过一项计划建立了外部质量控制,该计划评估进行免疫血液学检测的血库和输血服务实验室的表现。该计划包括向参与的血库或服务机构发送细胞面板,这些是先前作为问题案例研究过的红细胞样本,但参与实验室不知道其结果。该计划最重要的流程是ABO血型鉴定、Rh血型鉴定、直接和间接抗人球蛋白试验以及输血前相容性试验。对2020年期间参与国家医疗中心血库免疫血液学质量控制计划的104个单位所获得的结果进行了观察性和回顾性研究。每45天发送一组细胞进行免疫血液学外部质量控制,在研究期间每个单位共发送9组。观察到总体结果符合该计划(79.6%),即注册单位的参与度有所下降。在满分100%的情况下,观察到参与单位的总体合规率为95.3%。所获得的结果证实了参与单位免疫血液学实验室的总体良好培训情况。然而,正如在任何外部控制计划中一样,很明显获得错误结果是任何实验室都可能面临的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af3/10399761/02b2c3cf1277/04435117-61-Suppl1-S59-f001.jpg

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本文引用的文献

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