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迷你种植体无痛植入所需浸润麻醉剂的最小体积:一项双侧对照临床试验

Minimum volume of infiltrative anesthetic required for pain-free placement of mini-implants: a split-mouth clinical trial.

作者信息

Felicita A Sumathi, Wahab Thameem U L

出版信息

Quintessence Int. 2023 Jan 13;54(1):16-22. doi: 10.3290/j.qi.b3512065.

DOI:10.3290/j.qi.b3512065
PMID:36378301
Abstract

OBJECTIVE

To determine the minimum volume of infiltrative anesthetic required for pain-free mini-implant placement in the maxillary buccal region by comparing the efficacy of 1.0 mL with 0.5 mL of 2% lignocaine with 1:200,000 epinephrine during mini-implant placement.

METHOD AND MATERIALS

This split-mouth study involved 19 healthy patients without systemic disease, recent history of allergy, or medications within the age group of 17 to 28 years belonging to both sexes requiring bilateral buccal mini-implants in the posterior maxilla. Lignocaine 2% with 1:200,000 epinephrine (0.5 mL and 1.0 mL) was randomly injected between the right and left side 30 minutes apart for each consecutive patient. Mini-implants were placed 5 minutes after the administration of the infiltrative anesthetic. The pain response was evaluated during mini-implant placement (T1), and 5 minutes (T2) and 10 minutes (T3) after mini-implant placement on both sides using a pain-rating scale. Descriptive statistics and a factorial repeated-measure analysis of variance were calculated for pain response, sex, and side of the jaw.

RESULTS

At T1, T2, and T3, 1.0 mL of anesthetic had a lesser pain score by 1.00, 1.00, and 0.58, respectively, compared to 0.5 mL, with 95% confidence intervals of 0.43 to 1.57 (P = .001), 0.49 to 1.51 (P = .000), and 0.08 to 1.08 (P = .024), respectively.

CONCLUSIONS

1.0 mL of 2% lignocaine with 1:200,000 epinephrine administered submucosally appears to provide better anesthesia than 0.5 mL during and after insertion of mini-implants. This study will help the operator administer the correct volume of infiltrative anesthetic thereby improving pain response, alleviating patient anxiety, and providing a better patient experience during and immediately after mini-implant placement.

摘要

目的

通过比较在微型种植体植入过程中,1.0 mL与0.5 mL含1:200,000肾上腺素的2%利多卡因的麻醉效果,确定在上颌颊侧区域进行无痛微型种植体植入所需的浸润麻醉最小体积。

方法和材料

这项双侧对照研究纳入了19名年龄在17至28岁之间、无全身疾病、近期无过敏史且未服用相关药物的健康患者,这些患者双侧上颌后牙颊侧均需要植入微型种植体。对于每位连续入组的患者,含1:200,000肾上腺素的2%利多卡因(0.5 mL和1.0 mL)在左右两侧分别间隔30分钟随机注射。在浸润麻醉给药5分钟后植入微型种植体。在微型种植体植入过程中(T1)以及植入后5分钟(T2)和10分钟(T3),使用疼痛评分量表对两侧的疼痛反应进行评估。对疼痛反应、性别和颌侧进行描述性统计和析因重复测量方差分析。

结果

在T1、T2和T3时,与0.5 mL相比,1.0 mL麻醉剂的疼痛评分分别低1.00、1.00和0.58,95%置信区间分别为0.43至1.57(P = .001)、0.49至1.51(P = .000)和0.08至1.08(P = .024)。

结论

黏膜下注射1.0 mL含1:200,000肾上腺素的2%利多卡因在微型种植体植入期间及植入后似乎比0.5 mL提供更好的麻醉效果。本研究将有助于操作人员给予正确体积的浸润麻醉剂,从而改善疼痛反应,减轻患者焦虑,并在微型种植体植入期间及植入后立即提供更好的患者体验。

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