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用于乳腺超声视频诊断的对比学习引导的多元注意力网络

Contrastive learning-guided multi-meta attention network for breast ultrasound video diagnosis.

作者信息

Huang Xiaoyang, Lin Zhi, Huang Shaohui, Wang Fu Lee, Chan Moon-Tong, Wang Liansheng

机构信息

Department of Computer Science, School of Informatics, Xiamen University, Xiamen, China.

School of Science and Technology, Hong Kong Metropolitan University, Hong Kong, Hong Kong SAR, China.

出版信息

Front Oncol. 2022 Oct 24;12:952457. doi: 10.3389/fonc.2022.952457. eCollection 2022.

DOI:10.3389/fonc.2022.952457
PMID:36387264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9650917/
Abstract

Breast cancer is the most common cause of cancer death in women. Early screening and treatment can effectively improve the success rate of treatment. Ultrasound imaging technology, as the preferred modality for breast cancer screening, provides an essential reference for early diagnosis. Existing computer-aided ultrasound imaging diagnostic techniques mainly rely on the selected key frames for breast cancer lesion diagnosis. In this paper, we first collected and annotated a dataset of ultrasound video sequences of 268 cases of breast lesions. Moreover, we propose a contrastive learning-guided multi-meta attention network (CLMAN) by combining a deformed feature extraction module and a multi-meta attention module to address breast lesion diagnosis in ultrasound sequence. The proposed feature extraction module can autonomously acquire key information of the feature map in the spatial dimension, whereas the designed multi-meta attention module is dedicated to effective information aggregation in the temporal dimension. In addition, we utilize a contrast learning strategy to alleviate the problem of high imaging variability within ultrasound lesion videos. The experimental results on our collected dataset show that our CLMAN significantly outperforms existing advanced methods for video classification.

摘要

乳腺癌是女性癌症死亡的最常见原因。早期筛查和治疗可有效提高治疗成功率。超声成像技术作为乳腺癌筛查的首选方式,为早期诊断提供了重要参考。现有的计算机辅助超声成像诊断技术主要依靠所选关键帧进行乳腺癌病变诊断。在本文中,我们首先收集并标注了一个包含268例乳腺病变超声视频序列的数据集。此外,我们通过结合变形特征提取模块和多元注意力模块,提出了一种对比学习引导的多元注意力网络(CLMAN),以解决超声序列中的乳腺病变诊断问题。所提出的特征提取模块能够在空间维度上自主获取特征图的关键信息,而设计的多元注意力模块则致力于在时间维度上进行有效信息聚合。此外,我们利用对比学习策略来缓解超声病变视频中成像变异性高的问题。在我们收集的数据集上的实验结果表明,我们的CLMAN明显优于现有的先进视频分类方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/8148b57e8931/fonc-12-952457-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/3d10d0df134e/fonc-12-952457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/b7ccadf8a2ad/fonc-12-952457-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/ee9924f8d358/fonc-12-952457-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/356313b1ba76/fonc-12-952457-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/8148b57e8931/fonc-12-952457-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/3d10d0df134e/fonc-12-952457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/b7ccadf8a2ad/fonc-12-952457-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/ee9924f8d358/fonc-12-952457-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/356313b1ba76/fonc-12-952457-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/9650917/8148b57e8931/fonc-12-952457-g005.jpg

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本文引用的文献

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Semi-supervised GAN-based Radiomics Model for Data Augmentation in Breast Ultrasound Mass Classification.基于半监督生成对抗网络的乳腺超声肿块分类数据增强放射组学模型
Comput Methods Programs Biomed. 2021 May;203:106018. doi: 10.1016/j.cmpb.2021.106018. Epub 2021 Feb 27.
2
Efficient Anomaly Detection with Generative Adversarial Network for Breast Ultrasound Imaging.基于生成对抗网络的乳腺超声成像高效异常检测
Diagnostics (Basel). 2020 Jul 4;10(7):456. doi: 10.3390/diagnostics10070456.
3
Comparison of Digital Breast Tomosynthesis and Digital Mammography for Detection of Breast Cancer in Kuwaiti Women.
数字乳腺断层合成摄影与数字乳腺钼靶摄影对科威特女性乳腺癌检测的比较。
Med Princ Pract. 2019;28(1):10-15. doi: 10.1159/000495753. Epub 2018 Nov 26.
4
A deep learning framework for supporting the classification of breast lesions in ultrasound images.一种用于支持超声图像中乳腺病变分类的深度学习框架。
Phys Med Biol. 2017 Sep 15;62(19):7714-7728. doi: 10.1088/1361-6560/aa82ec.
5
Computer-Aided Diagnosis with Deep Learning Architecture: Applications to Breast Lesions in US Images and Pulmonary Nodules in CT Scans.基于深度学习架构的计算机辅助诊断:在超声图像乳腺病变及CT扫描肺结节中的应用
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