Parashar Rashmi, Bajpayee Archana, Mishra Vibha, Gupta Anubhav
Department of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.
J Family Med Prim Care. 2022 Jul;11(7):4048-4050. doi: 10.4103/jfmpc.jfmpc_2435_21. Epub 2022 Jul 22.
Development of severe fetal anemia due to red cell destruction in intrauterine life, most commonly implicated with hemolytic disease of fetus or newborn. Untreated cases lead to hydrops and even death of newborn. We are reporting a case of severe fetal anaemia successfully delivered after intrauterine transfusion. A 28-year-old female having bad obstetric history G10 P3600, came to our fetal unit at 23 + 4 weeks gestation. Middle cerebral artery peak systolic velocity (MCA PSV) value was 2.2 mom before 1 intrauterine procedure. Subsequent intrauterine session was planned at 1-2 week interval. After completion of 3 intrauterine transfusion, MCA PSV value was 0.8 mom and baby was delivered at 32 + 1 week via lower segment cesarean section. Intervention at appropriate time, appropriate volume of selected unit and appropriate rate of transfusion definitely improves perinatal outcome.
胎儿期因红细胞破坏导致严重胎儿贫血,最常见于胎儿或新生儿溶血病。未经治疗的病例会导致胎儿水肿甚至新生儿死亡。我们报告一例经宫内输血后成功分娩的严重胎儿贫血病例。一名28岁女性,不良产科史为G10 P3600,孕23 + 4周时前来我们的胎儿治疗中心。在进行1次宫内操作前,大脑中动脉收缩期峰值流速(MCA PSV)值为2.2 mom。随后计划每隔1 - 2周进行一次宫内操作。在完成3次宫内输血后,MCA PSV值为0.8 mom,婴儿于32 + 1周通过下段剖宫产分娩。在适当时间进行干预、选择合适的输血量和合适的输血速度肯定能改善围产期结局。