Department of Health Management and Policy, School of Public Health, Capital Medical University, Beijing, China.
China Center for Health Development Studies, Peking University, Beijing, China.
Front Public Health. 2022 Nov 1;10:864482. doi: 10.3389/fpubh.2022.864482. eCollection 2022.
This study aimed to investigate maternal preferences for gestational diabetes mellitus (GDM) screening options in rural China to identify an optimal GDM screening strategy.
Pregnant women at 24-28 gestational weeks were recruited from Shandong province, China. A discrete choice experiment (DCE) was conducted to elicit pregnant women's preferences for GDM screening strategy defined by five attributes: number of blood draws, out-of-pocket costs, screening waiting-time, number of hospital visits, and positive diagnosis rate. A mixed logistic model was employed to quantify maternal preferences, and to estimate the relative importance of included attributes in determining pregnant women's preferences for two routinely applied screening strategies ("one-step": 75 g oral glucose tolerance test [OGTT] and "two-step": 50 g glucose challenge-test plus 75 g OGTT). Preference heterogeneity was also investigated.
= 287 participants completed the DCE survey. All five predefined attributes were associated with pregnant women's preferences. Diagnostic rate was the most influential attribute (17.5 vs. 8.0%, OR: 2.89; 95%CI: 2.10 to 3.96). When changes of the attributes of "two-step" to "one-step" strategies, women's uptake probability from full "two-step" to "one-step" significantly increased with 71.3% (95%CI: 52.2 to 90.1%), but no significant difference with the first step of "two-step" (-31.0%, 95%CI: -70.2 to 8.1%).
Chinese pregnant women preferred the "one-step" screening strategy to the full "two-step" strategy, but were indifferent between "one-step" and the first step of "two-step" strategies.
本研究旨在探讨中国农村地区孕妇对妊娠期糖尿病(GDM)筛查方案的偏好,以确定最佳的 GDM 筛查策略。
本研究从山东省招募了 24-28 孕周的孕妇。采用离散选择实验(DCE)来评估孕妇对 GDM 筛查策略的偏好,该策略由五个属性定义:采血次数、自付费用、筛查等待时间、就诊次数和阳性诊断率。采用混合逻辑回归模型来量化孕妇的偏好,并估计纳入的属性在确定孕妇对两种常规应用的筛查策略(“一步法”:75 g 口服葡萄糖耐量试验[OGTT]和“两步法”:50 g 葡萄糖挑战试验加 75 g OGTT)的偏好中的相对重要性。还调查了偏好异质性。
= 287 名参与者完成了 DCE 调查。所有五个预设属性均与孕妇的偏好相关。诊断率是最具影响力的属性(17.5%对 8.0%,OR:2.89;95%CI:2.10 至 3.96)。当“两步法”的属性变化为“一步法”策略时,从完全“两步法”转为“一步法”的女性接受率显著增加了 71.3%(95%CI:52.2 至 90.1%),但与“两步法”的第一步(-31.0%,95%CI:-70.2 至 8.1%)相比没有显著差异。
中国孕妇更喜欢“一步法”筛查策略而不是完全的“两步法”策略,但对“一步法”和“两步法”的第一步策略之间没有明显差异。