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母体对妊娠期糖尿病筛查策略的选择和偏好:使用离散选择实验的探索性研究。

Maternal choices and preferences for screening strategies of gestational diabetes mellitus: A exploratory study using discrete choice experiment.

机构信息

Department of Health Management and Policy, School of Public Health, Capital Medical University, Beijing, China.

China Center for Health Development Studies, Peking University, Beijing, China.

出版信息

Front Public Health. 2022 Nov 1;10:864482. doi: 10.3389/fpubh.2022.864482. eCollection 2022.

Abstract

AIMS

This study aimed to investigate maternal preferences for gestational diabetes mellitus (GDM) screening options in rural China to identify an optimal GDM screening strategy.

METHODS

Pregnant women at 24-28 gestational weeks were recruited from Shandong province, China. A discrete choice experiment (DCE) was conducted to elicit pregnant women's preferences for GDM screening strategy defined by five attributes: number of blood draws, out-of-pocket costs, screening waiting-time, number of hospital visits, and positive diagnosis rate. A mixed logistic model was employed to quantify maternal preferences, and to estimate the relative importance of included attributes in determining pregnant women's preferences for two routinely applied screening strategies ("one-step": 75 g oral glucose tolerance test [OGTT] and "two-step": 50 g glucose challenge-test plus 75 g OGTT). Preference heterogeneity was also investigated.

RESULTS

= 287 participants completed the DCE survey. All five predefined attributes were associated with pregnant women's preferences. Diagnostic rate was the most influential attribute (17.5 vs. 8.0%, OR: 2.89; 95%CI: 2.10 to 3.96). When changes of the attributes of "two-step" to "one-step" strategies, women's uptake probability from full "two-step" to "one-step" significantly increased with 71.3% (95%CI: 52.2 to 90.1%), but no significant difference with the first step of "two-step" (-31.0%, 95%CI: -70.2 to 8.1%).

CONCLUSION

Chinese pregnant women preferred the "one-step" screening strategy to the full "two-step" strategy, but were indifferent between "one-step" and the first step of "two-step" strategies.

摘要

目的

本研究旨在探讨中国农村地区孕妇对妊娠期糖尿病(GDM)筛查方案的偏好,以确定最佳的 GDM 筛查策略。

方法

本研究从山东省招募了 24-28 孕周的孕妇。采用离散选择实验(DCE)来评估孕妇对 GDM 筛查策略的偏好,该策略由五个属性定义:采血次数、自付费用、筛查等待时间、就诊次数和阳性诊断率。采用混合逻辑回归模型来量化孕妇的偏好,并估计纳入的属性在确定孕妇对两种常规应用的筛查策略(“一步法”:75 g 口服葡萄糖耐量试验[OGTT]和“两步法”:50 g 葡萄糖挑战试验加 75 g OGTT)的偏好中的相对重要性。还调查了偏好异质性。

结果

= 287 名参与者完成了 DCE 调查。所有五个预设属性均与孕妇的偏好相关。诊断率是最具影响力的属性(17.5%对 8.0%,OR:2.89;95%CI:2.10 至 3.96)。当“两步法”的属性变化为“一步法”策略时,从完全“两步法”转为“一步法”的女性接受率显著增加了 71.3%(95%CI:52.2 至 90.1%),但与“两步法”的第一步(-31.0%,95%CI:-70.2 至 8.1%)相比没有显著差异。

结论

中国孕妇更喜欢“一步法”筛查策略而不是完全的“两步法”策略,但对“一步法”和“两步法”的第一步策略之间没有明显差异。

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