Valfré Laura, Conforti Andrea, Morini Francesco, Patel Neil, Bevilacqua Francesca, Cianci Maria Chiara, Bagolan Pietro, Braguglia Annabella
Neonatal Surgery Unit, Medical and Surgical Department of Fetus-Newborn-Infant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Neonatal Surgery Unit, Meyer Children Hospital, Florence, Italy.
Front Pediatr. 2022 Oct 26;10:977354. doi: 10.3389/fped.2022.977354. eCollection 2022.
In patients affected by CDH, survival beyond the neonatal period continues to increase thanks to technological and pharmacological improvements. Conversely, patients, families and caregivers are more and more frequently facing "new" complex late comorbidities, including chronic pulmonary and cardiac dysfunctions, neurodevelopmental challenges, and specific nutritional requirements, that often require ongoing long-term medical or surgical care. Therefore, late morbidity is now a key focus in clinical care of CDH. The aims of this paper are to stress some of the most important "unsolved problems" for CDH patients at long-term follow-up.
在患有先天性膈疝(CDH)的患者中,由于技术和药理学的进步,新生儿期后的生存率持续提高。相反,患者、家庭和护理人员越来越频繁地面临“新的”复杂晚期合并症,包括慢性肺和心脏功能障碍、神经发育挑战以及特殊的营养需求,这些往往需要持续的长期医疗或手术护理。因此,晚期发病率现在是CDH临床护理中的一个关键重点。本文的目的是强调在长期随访中CDH患者一些最重要的“未解决问题”。