MacGregor A J, Hart P
J Antimicrob Chemother. 1986 Jul;18(1):113-7. doi: 10.1093/jac/18.1.113.
Salivary samples were examined for a period three weeks before, and three weeks after the administration of 3 g of amoxycillin in ten volunteers. There was a marked drop in the concentration of streptococci in all subjects in the first 4 h but most had substantially recovered within 48 h. All had recovered at seven days. No strains were resistant to 1 mg/l amoxycillin in the pre-treatment control series, and no resistant streptococci emerged.
在10名志愿者服用3克阿莫西林之前3周和之后3周对唾液样本进行了检测。在最初4小时内,所有受试者口腔中链球菌浓度均显著下降,但大多数在48小时内基本恢复。7天时所有人都已恢复。在治疗前的对照样本系列中,没有菌株对1毫克/升阿莫西林耐药,也没有出现耐药性链球菌。