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健康青少年机动车事故继发毛霉菌病感染的成功管理:一例报告

Successful management of mucormycosis infection secondary to motor vehicle accident in a healthy adolescent: A case report.

作者信息

Shah Hemali, Chisena Ernest, Nguyen Brittany, Tristram Debra, Bialowas Christie

机构信息

Albany Medical College, 47 New Scotland Avenue, Albany, NY, 12208, USA.

Albany Medical Center Division of Orthopedic Surgery, 50 New Scotland Avenue, Albany, NY, 12208, USA.

出版信息

Med Mycol Case Rep. 2022 Nov 2;38:36-40. doi: 10.1016/j.mmcr.2022.10.004. eCollection 2022 Dec.

Abstract

Mucormycosis in healthy adolescents is a rare etiology of infection that does not have a commonly known protocol for management. This report describes an adolescent male who developed soft tissue mucormycosis secondary to a motor vehicle accident with severe lower extremity injuries. Treatment involved topical amphotericin B washouts and beads, serial aggressive debridement, and isavuconazole. To our knowledge, this is one of few documented cases of successful lower extremity salvage in an immunocompetent adolescent infected with mucormycosis and treated with isavuconazole.

摘要

健康青少年发生毛霉病是一种罕见的感染病因,目前尚无广为人知的治疗方案。本报告描述了一名青少年男性,他因机动车事故导致严重下肢损伤后发生了软组织毛霉病。治疗包括局部用两性霉素B冲洗和珠剂、多次积极清创以及使用艾沙康唑。据我们所知,这是为数不多的记录在案的免疫功能正常的青少年感染毛霉病并用艾沙康唑治疗后成功挽救下肢的病例之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14aa/9647094/cdc3c4bdc762/gr1.jpg

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